Insulin Treatment Flashcards

1
Q

What is the function of analogue insulin?

A

It has been manipulated to alter rates of absorption and persistence in the circulation

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2
Q

Give an example of a human short acting insulin?

A

Actrapid

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3
Q

Give an example of a human long acting insulin?

A

Insulatard

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4
Q

Give 2 examples of an analogue rapid acting insulin?

A

Humalog or Novorapid

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5
Q

Give 2 examples of an analogue long acting insulin?

A

Lantus or Levemir

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6
Q

What can short acing insulins be used for?

A

Pre-meal injections, during labour or medical emergencies

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7
Q

How soon will short acting insulin analogues begin to work? How long will they last?

A

10-15 mins // 4-5 hours

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8
Q

How soon will short acting human insulin begin to work? How long will they last?

A

30-60 mins // 5-8 hours

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9
Q

Which type of insulin is more likely to cause hypoglycaemia?

A

Human

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10
Q

When will human long acting basal insulins peak?

A

4-6 hours after administration

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11
Q

Most patients should be on what insulin therapy?

A

Long acting basal analogue insulin e.g. lantus/levemir

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12
Q

Patients will be taught to match their prandial insulin dose to what?

A

Carbohydrate intake, pre-meal glucose, anticipated activity

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13
Q

What should the pre-meal target of glucose be?

A

3.9-7.2mmol/l

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14
Q

What is the target of glucose after the beginning of a meal?

A

< 10mmol/l

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15
Q

What is the function of a basal bolus regimen?

A

Mimics normal endogenous insulin production

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16
Q

What insulins are used in a basal bolus?

A

A long acting (basal) insulin and a rapid acting (bolus) insulin

17
Q

When is the rapid acting insulin given in a basal bolus regimen?

A

With each meal

18
Q

When is the long acting insulin given in a basal bolus regimen?

A

Before bed

19
Q

What is the most flexible insulin regimen?

A

Basal bolus

20
Q

What injections will you take in a bi-daily regimen?

A

2 injections of a mix of short and intermediate acting insulin

21
Q

Who is a bi-daily insulin regimen suitable for?

A

People with a consistent routine

22
Q

Who is a once daily insulin dose used in?

A

Type 2 diabetics on medication also

23
Q

What type of insulin is used in a once daily regimen?

A

Long acting peak less insulin

24
Q

When should once daily insulin be taken?

A

Before breakfast

25
Q

When should twice daily insulin be taken?

A

One at breakfast and one at dinner

26
Q

When is IV insulin used?

A

DKA, HHS, acute illness and fasting patients

27
Q

What is the target HbA1c?

A

53-58mmol/mol

28
Q

What should you always check insulin injection sites for? What should patients do to avoid this complication?

A

Lipohypertrophy // Patients should change the sites of their injections and always use clean needles