Insulin Treatment Flashcards

1
Q

What is the function of analogue insulin?

A

It has been manipulated to alter rates of absorption and persistence in the circulation

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2
Q

Give an example of a human short acting insulin?

A

Actrapid

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3
Q

Give an example of a human long acting insulin?

A

Insulatard

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4
Q

Give 2 examples of an analogue rapid acting insulin?

A

Humalog or Novorapid

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5
Q

Give 2 examples of an analogue long acting insulin?

A

Lantus or Levemir

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6
Q

What can short acing insulins be used for?

A

Pre-meal injections, during labour or medical emergencies

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7
Q

How soon will short acting insulin analogues begin to work? How long will they last?

A

10-15 mins // 4-5 hours

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8
Q

How soon will short acting human insulin begin to work? How long will they last?

A

30-60 mins // 5-8 hours

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9
Q

Which type of insulin is more likely to cause hypoglycaemia?

A

Human

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10
Q

When will human long acting basal insulins peak?

A

4-6 hours after administration

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11
Q

Most patients should be on what insulin therapy?

A

Long acting basal analogue insulin e.g. lantus/levemir

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12
Q

Patients will be taught to match their prandial insulin dose to what?

A

Carbohydrate intake, pre-meal glucose, anticipated activity

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13
Q

What should the pre-meal target of glucose be?

A

3.9-7.2mmol/l

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14
Q

What is the target of glucose after the beginning of a meal?

A

< 10mmol/l

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15
Q

What is the function of a basal bolus regimen?

A

Mimics normal endogenous insulin production

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16
Q

What insulins are used in a basal bolus?

A

A long acting (basal) insulin and a rapid acting (bolus) insulin

17
Q

When is the rapid acting insulin given in a basal bolus regimen?

A

With each meal

18
Q

When is the long acting insulin given in a basal bolus regimen?

A

Before bed

19
Q

What is the most flexible insulin regimen?

A

Basal bolus

20
Q

What injections will you take in a bi-daily regimen?

A

2 injections of a mix of short and intermediate acting insulin

21
Q

Who is a bi-daily insulin regimen suitable for?

A

People with a consistent routine

22
Q

Who is a once daily insulin dose used in?

A

Type 2 diabetics on medication also

23
Q

What type of insulin is used in a once daily regimen?

A

Long acting peak less insulin

24
Q

When should once daily insulin be taken?

A

Before breakfast

25
When should twice daily insulin be taken?
One at breakfast and one at dinner
26
When is IV insulin used?
DKA, HHS, acute illness and fasting patients
27
What is the target HbA1c?
53-58mmol/mol
28
What should you always check insulin injection sites for? What should patients do to avoid this complication?
Lipohypertrophy // Patients should change the sites of their injections and always use clean needles