Insulin,glacgon Flashcards
Where is glucose absorbed?
In the GI tract
What is glucose really important for?
The brain as it is its only energy source
Where does glucose go after it enters the GI tract?
The circulation
What is glucose used for?
To fuel metabolism in many tissues
What are the main sites of glucose storage?
Muscle and liver
How is glucose used to fuel metabolism?
Used to produce ATP (energy)
How is glucose stored in the liver and muscle?
As glycogen
What happens to glucose after eating?
Increases, increasing circulation
What happens when glucose increases?
More ATP can be produced and increased O2 demand
What happens when glucose is scarce?
Glucose released from glycogen store
Amino acid raise and insulin and glucagon?
Insulin release which promotes amino acid uptake but glucose inappropriately but also glucagon so compensates.
Gluconeogenesis
Making glucose from lipids and amino acids.
Glycogen stores -> fat -> proteins
What does glucagon do? (2)
Promotes glucose release from glycogen stores (mainly liver)
Promotes gluconeogenesis to convert lipids and amino acids in to glucose
Fed state
Insulin dominates
- Inc glucose oxidation
- Inc glycogen synthesis
- Inc fat synthesis
- Inc protein synthesis
Fasting state
Glycogen dominates
- Inc glycogenesis
- Inc gluconeogenesis
- Inc ketogenesis
