Autoinjector pens and pre-filled syringes Flashcards
What do patient want in injector pens (4)
Painless
Reliable dose
Easy to use
Safe to use and store
Advantages of autoinjectors, pens and pre-filled syringes (3)
Improved safety
Improved dosing accuracy
Increased patient compliance
3 injector devices
Single use
Disposable (until drug finished)
Reusable
Autoinjector considerations
Needle length (IM/SC, needle also in pen) Method of administration Designed for people with no medical expertise
Autoinjector testing for IM
Liquid cannot be compressed
Solution pressurized at varying degrees that can cause the solution to be expelled by varying degrees.
(Ballistic gelatin studies, porcine studies)
Advantages of autoinjectors (5)
-Viscous solutions – can self-injects
-Risk prevention form needle stick injury
-Safe/accurate drug delivery device
-Can overcome needle phobia as needle is shielded
-Reduced healthcare time (less training)
(Easy grip and expiration date clear)
What does higher gauge mean for needle size?
Higher = thinner
3 advantages of thinner needles
Less painful
Less damage to skin
Easier insertion
Siliconization interactions and 3 advantages
- Barrier between glass and drug formulation
- Prevents adsorption to glass surface
- Improved drain ability
- Lubricates the syringe barrel.
Why should you continue with the same brand of insulin?
The dosing may vary depending on device. So, patient should be aware if there is change.
Advantages of pre-filled syringes
- Fixed dosages
- Potential for safe administration
- Compared to vials – reduced overfill – decreased costs to pharmacy
- Personalized drugs to small populations
Syringe material
Glass- excellent barrier properties and regulatory use
Plastic – stability and inert properties
