Autoinjector pens and pre-filled syringes Flashcards

1
Q

What do patient want in injector pens (4)

A

Painless
Reliable dose
Easy to use
Safe to use and store

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2
Q

Advantages of autoinjectors, pens and pre-filled syringes (3)

A

Improved safety
Improved dosing accuracy
Increased patient compliance

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3
Q

3 injector devices

A

Single use
Disposable (until drug finished)
Reusable

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4
Q

Autoinjector considerations

A
Needle length (IM/SC, needle also in pen)
 Method of administration
 Designed for people with no medical expertise
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5
Q

Autoinjector testing for IM

A

Liquid cannot be compressed
Solution pressurized at varying degrees that can cause the solution to be expelled by varying degrees.
(Ballistic gelatin studies, porcine studies)

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6
Q

Advantages of autoinjectors (5)

A

-Viscous solutions – can self-injects
-Risk prevention form needle stick injury
-Safe/accurate drug delivery device
-Can overcome needle phobia as needle is shielded
-Reduced healthcare time (less training)
(Easy grip and expiration date clear)

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7
Q

What does higher gauge mean for needle size?

A

Higher = thinner

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8
Q

3 advantages of thinner needles

A

Less painful
Less damage to skin
Easier insertion

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9
Q

Siliconization interactions and 3 advantages

A
  • Barrier between glass and drug formulation
  • Prevents adsorption to glass surface
  • Improved drain ability
  • Lubricates the syringe barrel.
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10
Q

Why should you continue with the same brand of insulin?

A

The dosing may vary depending on device. So, patient should be aware if there is change.

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11
Q

Advantages of pre-filled syringes

A
  • Fixed dosages
  • Potential for safe administration
  • Compared to vials – reduced overfill – decreased costs to pharmacy
  • Personalized drugs to small populations
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12
Q

Syringe material

A

Glass- excellent barrier properties and regulatory use

Plastic – stability and inert properties

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