insulin Flashcards
what is the target HbA1c for adults with type 1 diabetes
48mmol/mol (6.5%)
What is the target HbA1c for adults with type 1 WITH CHRONIC KIDNEY DISEASE not treated with dialysis
48 - 64 mmol/mol
what are the three types of insulin and define them
- Human insulin = Produced by recombinant DNA technology and have the same amino acid sequence as endogenous human insulin
- human insulin analogues = litch human insulin that has been modified to produce a specific desired kinetic characteristic
- Animal insulin = no longer in use
what is rapid acting insulin
insulin that is Given shortly before or after meals as they are used to replicate the normal insulin produced by the body in response to the glucose absorbed from a meal or sugary drink
what is the onset of action and duration of action of rapid acting insulin
Onset = 15 mins
Duration = 2 - 5 hours
what are the examples of rapid acting and their brands
> insulin ASPART = novo rapid
Insulin glulisine = Apidra
insulin LISPRO = humalog . luvmedj
what are short acting insulin
-
what is the onset of action and duration of action of subcutaneous SHORT acting insulin
Onset = 30 - 60 mins
Duration = 8 hours
what are the examples of short acting insulin
> Actrapid
Human insulin - Humilin S
what is intermediate acting insulin
❤️They mimic the effect of endogenous basal insulin (insulin that is secreted continuously throughout the day).
❤️They have a slow onset of action and a long duration of action
what is the onset and duration of action of intermediate acting insulin
Onset = 1 - 2 hours, max effects 3 - 12 hours
Duration = 11 = 24 hours
what are the example of intermediate insulin
Isophane insulin
- Humilin I
- INSUMAN BASAL
- Insulatard
what is the benefit of insulatard
it has less than 1mmol sodium (23 mg) per dose so it is essentially sodiu, free
what is it called when isophane insulin is mixed with a short acting insulin
biphasic insulin that may be either pre mixed or not
what are the examples of biphasic insulin
> Biphasic isophane insulin
> Biphasic insulin ASPART - novomix
> Biphasic insulin LISPRO - humalog mix
