Insomnia Flashcards
INSOMNIA: IS IT A PROBLEM?
Who has slept poorly at least once?
Who sleeps poorly regularly?
Who has a sleeping problem?
Who has slept poorly at least once? 95% of the population
Who sleeps poorly regularly? 30% of the population
Who has a sleeping problem? 10% of the population
WHY DO WE NEED SLEEP?
We still don’t really know
We know what happens if you don’t sleep:
> Physical: Inflammation processes are disturbed
> Cognitive: Poor memory
> Emotional: Mood swings + irritable
> Ultimately: death
HOW MUCH SLEEP DO WE NEED?
WHAT IS SLEEP?
5 fases = 1 cycle = about 1,5 hr Every night: 4 a 5 cycles
Start of the night: most of the deep sleep
the phases are: awake, REM-sleep, snooze, light sleep, moderate deep sleep and deep sleep
WHAT MAKES US SLEEP?
2 mechanisms
- Circadian rhythm (C)
- Regulates hormones in our body (e.g. melatonine)
- Normally slightly longer than 24hrs
- Regulated by cues = “zeitgebers” e.g. light
- Also regulates appetite, core body temperature etc.
- Homeostatic sleep process (S)
- Accumulation of sleep inducing substances in the brain during waking hours
- The longer you are awake à the more tired
- During sleep you break down the substances
WHY DO WE NOT SLEEP? (hyperarousal)
Hyperarousal
Impossible to ‘switch of’
During acute stress periods
Or chronic stressors:
- Too busy during the day
- Ruminating too much
- Then: Ruminating about sleep
- Develop bad sleep habits: Circle!
Likelihood of sleep disturbance (types of insomnia)
WHY DO WE NOT SLEEP?
- individual vulnerability
- precipitating factors
- perpetuating factors
In summary:
Individual vulnerability > Biological, personality
Precipitating factors > Stress and life events
Perpetuating factors > Dysfunctional sleep habits: going to bed early (or very late), to lie in in the morning, take a nap etc
INSOMNIA: WHEN IS IT A DISORDER?
DSM-IV: sleep disorder
DSM-5: sleep- wake disorder
DSM-5: Insomnia Disorder:
- Difficulty initiating or maintaining sleep (at least 30 minutes per night)
- At least 3 nights a week
- At least 3 months
- Causes clinically significant distress or impairment in daytime functioning
Other sleep disorders:
- Sleepapnea = breathing stops §
- Restless legs
- Circadian rhythm disorders=sleep at the wrong moment §
- Parasomnia = nightmares
- Hypersomnolence=excessive sleepiness (during day)
How (with what) do you measure sleep/insomnia?
Objective:
- Polysomnography: gold standard
- Actigraphy: NB not Fitbit etc
Subjective:
- sleepdiary
Various sleep estimates:
- Sleep Onset Latency – time to fall asleep
- Totale Sleep Time
- Sleep Efficiency - % asleep of total time in bed
- Wake After Sleep Onset
INSOMNIA: HOW DO YOU MEASURE IT?
(Objective v. subjective)
Objective ≠ subjective
Good sleepers: overestimate hours of sleep
Poor sleepers: underestimate hours of sleep
INSOMNIA: HOW DO YOU MEASURE IT? (Questionnaire)
Questionnaire: Insomnia Severity Index
INSOMNIA: CONSEQUENCES
- Tired
- Mood swings
- Poor concentration
- Absence school / work
- More use of health care
- Higher risk on other disorders > Depression > Anxiety > Cardiovascular > Mortality
TREATMENT: MEDICATION
Sleep medication (called hypnotics): OK, if it is every now and then
- If long-term: > dependent > Not alert > Chance on accidents
Antidepressants
- More and more used
- Currently trials in NL (amitryptiline)
Melatonine
- Only effective in jetlag
- Might enhance insomnia