insluin types

Question 1

Lispro

Answer 1

Humalog - rapid acting

proline and lysine switch places with eachother from human inslulin in drug

Question 2

aspart

Answer 2

Novalog- rapid acting
homologus with human insulin except for one single amino acid and is produced from baker’s yeast. proline replaced with aspartic acid

Question 3

glulisine

Answer 3

apidra- rapid acting
rapid acting analogues
made from e coli but asparagine is replaced by lysine and lysine replaced by gluramic acid

Question 4

regular insulin

Answer 4

soluble, short acting

Question 5

NPH

Answer 5

isophane- intermediate acting 10 hours

Question 6

glargine

Answer 6

Lantus- long acting (longest acting 20-24 hours)
when injected it is neutralized so formation of micro-precipitates from which small amounts of Lantus are released over time.
24 hour insulin with no peaks

Question 7

detemir

Answer 7

levemir - long acting (14-20hr)

threonine has been taken out and fatty acid chain added