Innate Immunity I Flashcards

1
Q

Nucleic Acid PAMPS

A
  • Double-stranded RNA
    • Viruses
  • CpG-containing DNA
    • bacteria, fungi, viruses
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2
Q

Cell Wall PAMPS

A
  • Lipopolysacharide, flagellin
    • Gram Negative bacteria
  • lipoteichoic acids
    • Gram Positive bacteria
  • Peptidoglycan, lipoproteins
    • bacteria
  • Manose, flucose rich polysaccharides, Beta-glucans
    • bacteria and fungi
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3
Q

Biosynthetic Commponents, PAMPS

A

N-formylated methionyl peptides

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4
Q

Gram Negative Cell wall

A
  • Lipopolysaccharide (LPS)
    • Porins tranverse
  • Outer membrane
  • lipoprteins
  • Peptidoglycans
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5
Q

Gram-Positive Cell wall

A
  • Teichoic acid
  • peptidoglycan
  • Lipoteichoic acid
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6
Q

Eyes

A

Washing of tears

Lysozyme

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7
Q

Skin

A
  • Anatomic barrier
  • antimicrobial secretions
  • dry
  • High salt concentration
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8
Q

Respiratory Tract

A
  • Mucus
  • Ciliated epithelium
  • Alveolar macrophages
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9
Q

Urinary Tract

A
  • Washing of urine
  • Acidity of urine
  • Lysozyme
  • Vaginal lactic acid
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10
Q

Digestive Tract

A
  • Stomach acidity
  • Normal flora
  • bile
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11
Q

Lysozyme

Function

Source

A
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12
Q
A
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