Caries

Question 1

Oral Innate Immunity

Answer 1

Mucosal dental barriers

Soluble antimicrobial factors in saliva & GCF

Inflammation by phagocytes :Neutrophil, macrophages, eosinophil

Question 2

Adaptive Immmunity in Oral cavity

Answer 2

Saliva: sIgA

GCF: IgG IgM

T effector cells in oral tissues

Question 3

Oral micro flora

Virus

Bacteria

Yeast

Answer 3

Virus: Cytomegaloviruses, herpes, hepatitis, Epstein-Barr

Bacteria: P prevotella, Fusobacterium, Actinobacillus, Actinomyces, Neisseria, Strep, Staph

Yeast: candida, saccharomyces

Question 4

Types of caries and organisms involved

Answer 4

Enamel- dental caries

Dentin- dentinal caries

root dentin- root caries

Organisms

Strep, lactobacillus, actinomyces (root)

Question 5

Gingivitis manifectations and microbes

Answer 5

Redness and swelling-inflammation

Actinomyces, Fusobacterium, Bacteroides, Prevotella

Question 6

Periodontitis manifestation/ types, organisms

Answer 6

Inflammation and either rapid (aggressive generalized or localized) or slower (chronic) destruction of tissue supporting gums

Aggregatibacter (localized)

Porphyromonas, Treponema, Tannerella, Fusobacterium, Prevotella

Question 7

Describe microbes responsible for caries

Answer 7

• Lactic acid bacteria
• Heterogenous family of good and bad
• All ferment sugars and form lactic acid as end product
• Lactic acid is less volatile than others and chelates calcium
• Facilitates demineralization of enamel
• Form glucose polymers (glucans) from sucrose via glucosyltransferase enzyme (GTF)
  *

Question 8

3 types of dental caries and microbes involved

Answer 8

• Enamel