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Infection and Immunity > Innate Immunity > Flashcards

Innate Immunity Flashcards

1
Q

Kill bacteria:

A

Pahocytosis/ degranulation/ NET

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2
Q

Kill parasites:

A

Degranulation/ cytokines

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3
Q

Promote inflammation:

A

Degranulation (Histamine/ Heparin)

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4
Q

Natural killer cell:

A

Kills infected/ cancer cells

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5
Q

T helper cells:

A

Provide help to B cells

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6
Q

T C Cytotoxic T cells:

A

Kill infected cells via MCHI

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7
Q

B cell:

A

Antibody production

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8
Q

Type of cells:

A

Innate, adaptive, interface

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9
Q

Innate response contains

A

Nk cells, macrophages, neutrophils, immature DC’s

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10
Q

Adaptive immune response contains:

A

B cells, CD4, CD8, mature DC

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11
Q

Innate mechanisms

A

Skin, mucosal surfaces, temperature, low pH, Chemical mediators

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12
Q

Skin:

A

Acidic environment inhibits growth of microbes, barrier

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13
Q

Mucosal surfaces:

A

Epithelial barrier, mucus traps foreign substances, cilia propel foreign substances out of the body

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14
Q

Temperature

A

Normal body temperature and fever responses inhibit growth of some pathogens

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15
Q

Low Ph

A

Acidity of stomach kills most invading microorganisms

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16
Q

Chemical mediators

A

Lysosyme, interferon, complement

17
Q

Cytokines Chemokines

A

enable migration of cells from blood vessels into the tissues, produced by many cells from blood vessels into tissue

18
Q

Antimicrobial peptides

A

Produced by phagocytes, lymphocytes, epithelial cells of GI and GU tracts, cells of the tracheobronchial tree

19
Q

Complement proteins

A

Primarily produced in liver, factor D in adipose tissue

20
Q

Interferons

A

Add resistance to viral replication

21
Q

Endocytose

A

Various cells internalise and break down foreign macromolecules

22
Q

Phagocytotic

A

Specialised cells that internalise, kill and digest whole microorganism

23
Q

Macrophages stationed at:

A

Strategic points where microbial invasion or accumulation of airborne particles are likely to be

24
Q

Alveolar macrophages

A

pulmonary alveolus of lungs

25
Q

Histiocytes

A

connective tissue

26
Q

kupffer cells

A

LIVER

27
Q

microglia

A

neural tissue

28
Q

Epithelioid Cells

A

Granulomas

29
Q

Osteoclasts

A

Bone

30
Q

Sinusoidal lining cells

A

spleen

31
Q

Mesangial cells

A

kidney

32
Q

Phagocytosis

A

Ingest and digest exogenous antigens, receptor mediated process, chemotaxis,

Infection and Immunity (3 decks)

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