Cells and organs of the immune system Flashcards
Immune system
Composed of cells, molecules, organs with purposed of defending body from foreign invaders.
distignuishes between self and nonself- good non self and bad non self
Immune System
Cells, molecules and organs that act to defend the body against foreign invaders
Type of responses
Recognition and response, Innate and adaptive immunity, Humoral and cellular
Innate immunity is
rapid
Adaptive immunity
slow
Innate immunity
Anatomic barriers, Physiologic barriers, phagocytic/ endocytic barriers, inflammatory barriers
adaptive immunity
antigenic challenge, high degree of specificity, diversity, memory, self/non self recognition
Activation of humoral and cell mediated immune system requires
cytokines made by Th cells
Take up of antigens by phagocytosis breaks into peptides bound to
MHC 2 interaction with TCellR of Th cell co- stimulatory signal
B cells mature in the
bone marrow, antigen binding receptor,
T cells mature in
Thymus, antigen binding molecule
Self Non self recognition
Central tolerance and peripheral tolerance
Primary- organs
Microenvironment for development and maturation of lymphocytes
Secondary organs
Trap antigen, mature lymphocytes and antigen interact
Lympatic system links
primary secondary lymphoid organs
