Inhibits nucleic acid synthesis

Question 1

Drug toxicity: not given to pregnant women because it can interfere with cartilage development in newborns

Answer 1

Quinolones (cipro)

Question 2

Drug toxicity: Red Man Syndrome

Answer 2

Rifampin

Question 3

Used to treat UTI

Answer 3

Antimetabolites

Question 4

What’s the mode of action of antimetabolies?

Answer 4

Sulfonamide: prevents folic acid synthesis in bacteria

Question 5

What’s the mode of action of Polymyxin?

Answer 5

Cell membrane injury

Question 6

Used to treat Pneumocystis pneumonia

Answer 6

Antimetabolites

Question 7

What’st he mode of action of Quinolones (cipro)?

Answer 7

Inhibits DNA gyrase; prevents DNA replication

Question 8

A topical agent mainly Gram - that causes cell membrane injury

Answer 8

Polymyxin

Question 9

What’s a broad spectrum drug that inhibits nucleic acid snythesis?

Answer 9

Quinolones (cipro)

Question 10

Used against Mycobacterium tuberculosis in combo with Isoniazid and Ethambutol.

Answer 10

Rifampin

Question 11

What’s the mode of action of Rifampin?

Answer 11

Inhibits RNA polymerase (prevents transcription)