Inhibits cell wall synthesis

Question 1

Vancomycin is only effective against Gram [?]

Answer 1

Gram +

Question 2

Drugs that inhibit synthesis of mycoloic acid

Answer 2

Isoniazid and Ethambutol

Question 3

Name two drugs used against tuberculosis.

Answer 3

Isoniazid and Ethambutol

Question 4

What are the classes that are non-beta lactam drugs that also inhibit cell wall synthesis?

Answer 4

Bacitracin and Vancomycin

Question 5

Which drug is resistant to penicillinase?

Answer 5

methicillin

Question 6

What is beta-lactamase (penicillinase)?

Answer 6

An enzyme which inactivates the penicillin

Question 7

What are ways to limit drug resistance?

Answer 7

1) Treat until all pathogens are destroyed [compliance] 2) Combination chemotherapy 3)only prescribe when necessary

Question 8

What inactivates the penicillinase made by bacteria?

Answer 8

clavulanic acid

Question 9

Name the 3 beta-lactam drugs that inhibit cell wall synthesis

Answer 9

Penicillins. Cephalosporins. Carbapenems

Question 10

What drug class is a broad spectrum that’s often effective in nosocomial infections?

Answer 10

carbapenems

Question 11

Penicillin is used primarily for?

Answer 11

Staph (Gram +), strep, and syphilis

Question 12

[Bacitracin]– What gram does it target? Route of administration? Mode of action?

Answer 12

Targets Gram +. Topical ointment. Inhibit cell wall synthesis.

Question 13

Which drug class works just like penicillin but is resistant to beta-lactamase enzyme?

Answer 13

Cephalosporins

Question 14

Name the three classes of cephalosporins

Answer 14

1st gen: generally for gram +. 2nd gen: also kills enterics. 3rd gen: kills Pseudomonas

Question 15

Last line of drug against Staph. aureus

Answer 15

Vancomycin