inhibitors of protein/rna synthesis Flashcards
1
Q
B) blocks binding of aminoacyl-tRNA to the A site
A
tetracycline
2
Q
B) prevents transition from translation initiation to chain elongation; also causes miscoding
A
streptomycin
3
Q
B) block the peptidyl transferase reaction
A
chloramphenicol
4
Q
B) binds in the exit tunnel of ribosome and inhibits elongation
A
erythromycin
5
Q
B) blocks initiation of RNA chains by binding to RNA pol.
A
rifamycin
6
Q
B/E) causes premature release of nascent polypeptide chains
A
puromycin
7
Q
B/E) binds to DNA and blocks the movement of RNA polymerase
A
actinomycin D
8
Q
E) blocks the A site of the 60S ribosome
A
harringtonine
9
Q
E) blocks the peptidyl transferase reaction
A
anisomycin
10
Q
E) blocks mRNA synthesis by binding preferentially to RNA pol II
A
a-amanitin
