Inhibitors of Protein or RNA synthesis in Bacteria

Question 1

Blocks binding of aminoacy-tRNA to A-sie of ribosome

Answer 1

Tetracycline

Question 2

prevents the transition from translation initiation to chain elongation and also causes miscoding

Answer 2

Streptomycin

Question 3

blocks the peptidyl transferase RXN on ribosmes

Answer 3

chloramphenicol

Question 4

binds in the exist channel of the ribosome and thereby inhibits elongation of the peptide chain

Answer 4

erythromycin

Question 5

blocks initiation of RNA chains by binding to RNA polymerase (prevents RNA synthesis

Answer 5

rifamycin