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Bacteriology > Inhibitors of Cell Wall Synthesis > Flashcards

Inhibitors of Cell Wall Synthesis Flashcards

1
Q

D-Cycloserine mechanism

A

Inhibits L-Ala–>D-Ala

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2
Q

D-Cycloserine targets

A

TB (second line bc of side effects)

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3
Q

Bacitracin mechanism

A

Blocks bactoprenol (lipid carrier)

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4
Q

Bacitracin targets

A

G+ cocci/bacilli
Neisseria
H. influenza
T. palladium

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5
Q

Bacitracin resistant

A

Enterobacteriaceae
Pseudomonas
Nocardia

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6
Q

Fosfomycin mechanism

A

Blocks transfer of NAG–NAM

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7
Q

Fosfomycin targets

A

Broad spectrum G+&G-

Uncomplicated UTIs

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8
Q

Fosfomycin resistant

A

Anaerobes

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9
Q

Vancomycin mechanism

A

Binds D-Ala–D-Ala

Blocks transglycosylase

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10
Q

Vancomycin targets

A

G+ only (narrow spectrum)

MRSE, MRSE, C. diff, Enterococci

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11
Q

Penicillin G/V targets

A

G+ aerobes besides staph

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12
Q

Penicillin G/V resistant

A

Staph, Gonococcus, Intracellular bacteria

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13
Q

Isoxazolyl penicillins

A

Oxacillin, Cloxacillin, dicloxacillin, nafcillin

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14
Q

Isoxazolyl targets

A

Staph

NOT MRSA

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15
Q

Aminopenicillins

A

Amoxicillin, ampicillin, augmentin, unasyn

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16
Q

Aminopenicillins target

A

G-

B-lactamase inhibitors extend spectrum

17
Q

Anti-pseudomonal penicillins

A

Ticarcillin, Carbenicillin, Piperacillin, Timentin

18
Q

Cephalosporins

A

More B-lactamase resistant than penicillins

19
Q

1st gen targets

A

Gram + cocci
Proteus
E. coli
Klebsiella

20
Q

2nd gen targets

A 
Gram + cocci
Haemophilus
Enterobacter
Neisseria
Proteus
E. coli
Klebsiella
21
Q

3rd gen targets

A

Life-threatening G- sepsis

22
Q

4th gen targets

A

Gram-

Nosocomial infections

23
Q

5th gen targets

A

G+, G-, no MRSA

24
Q

Carbapanem targets

A

G+ cocci, G-rods, anaerobes

B-lactamase resistant so broad spectrum

25
Q

Monobactam targets

Bacteriology (8 decks)

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