inhibidores de la sintesis de proteinas 50s Flashcards

1
Q

macrólidos

A

Eritromicina, Claritromicina, Azitromicina, Telitromicina

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2
Q

macrolidos MoA

A

Bloqueo de peptidil transferasa
Inhibición de la translocación de la base nitrogenada

bactericida y bacterioestatico

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3
Q

macrolidos espectro

A

grampositivos; ➕ gramnegativos; atípicos. Estreptococos del grupo A, neumococos

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4
Q

macrolidos indicaciones

A

chancro
respiratoria
legionario
Bartonella pertussis, que causa la tosferina.

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5
Q

Lincosamidas (Clindamicina) MoA

A

inh la translocación

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6
Q

Lincosamidas (Clindamicina) espectro

A

grampositivos; ➕➕➕ anaerobios. Estreptococos y SARM (además toxinas). B. fragilis y Clostridium perfringens

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7
Q

Lincosamidas (Clindamicina) indicaciones

A

Gangrena gaseosa, fascitis necrosante, infecciones pulmonares y pleurales anaerobias.

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8
Q

Lincosamidas (Clindamicina) EA

A

megacolo toxico
colitis pseudomembranosa

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9
Q

Cloranfenicol MoA

A

bloqueo de enzima peptidil transferasa

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10
Q

Cloranfenicol indicaciones

A

meningitis 2da o abcesos cerebrales
oculares bebe gris

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11
Q

clorafenicol

A

sindrome del bebe gris

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12
Q

Oxazolidinonas MoA

A

nhiben la síntesis de proteínas uniéndose a la subunidad 50S del ribosoma e impidiendo que se combine con la subunidad 30S para formar el complejo de iniciación.

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