Inheritance Patterns Flashcards
How are males represented in a pedigree drawing?
Squares
How are females represented in a pedigree drawing?
Circle
How are siblings represented in a pedigree drawing?
Line above them
How are partners represented in a pedigree drawing?
Line between them
How are affected people represented in a pedigree drawing?
Shaded in
How are carriers represented in a pedigree drawing?
Dots in their shape
How are children represented in a pedigree drawing?
Line down
How are consanguineous partners represented in a pedigree drawing?
Double line
What does SB mean in a pedigree drawing?
Still born
How are people of unknown sex represented in a pedigree drawing?
Diamond
How are miscarriages represented in a pedigree drawing?
Triangle
How is an abortion represented in a pedigree drawing?
Triangle with a line through
How are foetus’ of unknown sex represented in a pedigree drawing?
Diamond with a P inside
How are identical twins represented in a pedigree drawing?
Horizontal line between two diagonal lines
How are non-identical twins represented in a pedigree drawing?
Two diagonal lines
What is penetrance?
The percentage of individuals that carry the mutation and develop symptoms of the disorder
Give some characteristics of autosomal dominant inheritance
- most affected individuals have an affected parent
- both sexes equally likely to inherit the allele
What is the risk for each child of an affected parent in autosomal dominant inheritance?
1/2