inheritance (2) Flashcards

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1
Q

what antigen and antibody does blood A produce?

A

antigen: A
antibody: anti-B
can only receive from blood A

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2
Q

what antigen and antibody does blood B produce?

A

antigen: B
antibody: anti-A
can only receive from blood B

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3
Q

what antigen and antibody does blood AB produce?

A

antigen: A and B
antibody: none
universal recipient, can only donate to blood AB

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4
Q

what antigen and antibody does blood O produce?

A

antigen: none
antibody: anti-A and anti-B
universal donor, can only receive from blood O

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5
Q

what is co-dominance?

A

both alleles contribute to the phenotype of the organism. both alleles are dominant. (e.g. coat colour of cattle)
(RW, TP)

[homozygous phenotype : heterozygous phenotype : homozygous phenotype]

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6
Q

what are multiple alleles?

A

more than 2 alleles responsible for a particular trait (e.g. blood type: A, B, O)

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7
Q

what is incomplete dominance?

A

one allele is not completely dominant over the other. the heterozygous phenotype is somewhere between the two homozygous phenotypes. (e.g. flower colour in snapdragons—heterozygous alleles result in pink flowers instead of red or white)

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8
Q

what are polygenic traits?

A

two or more genes control a trait (e.g. skin colour in humans)

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9
Q

what is the definition of mutation?

A

a sudden change in the structure of a gene/DNA or in the chromosome number (each somatic cell: 46 chromosomes, each gamete: 23 chromosomes)

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10
Q

what is the definition of mutagens?

A

factors which increase the chance of mutations (physical and chemical)

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11
Q

what are some physical mutagens?

A
  • high energy electromagnetic radiation (UV light, X-rays, gamma rays)
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12
Q

what are some chemical mutagens?

A
  • food preservatives
  • certain constituents of tobacco
  • pesticides
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13
Q

what is the definition of chromosome mutation?

A

chromosomes are altered and affects the number of chromosomes in a cell

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14
Q

what is the definition of gene mutation?

A

gene may be modified in DNA sequence. gene mutation produces variation between individuals as it results in new alleles of genes. if the gene mutation occurs during gamete production, the resulting genetic change can be inherited by the offspring (progeny)

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15
Q

an example of gene mutation: sickle cell anaemia, explain

A
  1. the mutation gene produces haemoglobin HbS instead of normal HbA due to a change in one amino acid (substitution for adenine for thymine → glutamine to valine)
  2. HbS molecules clump together into a sickle shape which interferes with the oxygen-carrying property of the cell
  3. HbS mutation is recessive and can only express itself in homozygous recessive conditions
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16
Q

what are the types of gene mutations?

A
  • substitution
  • deletion
  • insertion
  • frameshift
17
Q

what is substitution (mutation)?

A

exchanged one base for another (single base mutations = point mutations) (e.g. adenine to thymine—sickle cell anaemia)

18
Q

what is deletion (mutation)?

A

a section of DNA is lost/deleted
(CTAAG → CTG)

19
Q

what is insertion (mutation)?

A

extra base pairs are inserted into a new place in the DNA
(CTGAAG → CTGTTAAG)

20
Q

what is frameshift (mutation)?

A

when deletions and insertions alter a protein-coding DNA such that the gene no longer makes sense
(e.g. THE FAT CAT → HEF ATC AT)