Inhalers and related drugs Flashcards

1
Q

MDI general information and instructions?

A

metered dose inhalers contain a hydrofluoroalkane propellant
• To use: shake 10 seconds → exhale fully → place inhaler one or two fingers from mouth → start inhaling as the button is pressed → finish inhalation → hold breath 10 seconds → exhale via nose → rinse mouth

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2
Q

DPI general info and instructions?

A

dry powder inhalers
• To use: exhale fully → make tight seal around inhaler → quick, deep inhale → hold breath 10 seconds → exhale via nose → rinse mouth

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3
Q

asthma definition?

A

inflammatory condition of the lungs caused by inflammatory mediators

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4
Q

inflammatory mediators?

A

histamine, leukotrienes, prostaglandins

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5
Q

bronchodilators vs. steroids:

A
  • Use bronchodilator first, then steroid to treat underlying cause
  • Inhaled bronchodilators; only treat symptoms
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6
Q

Beta-2 agonists details:

A

sympathomimetics

stimulate beta-2 receptors in the lungs → bronchodilaton

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7
Q

rescue inhaler details

A
  • Onset of 5 minutes

* Metered dose inhalers; used QID

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8
Q

rescue inhaler generics?

A
albuterol, levalbuterol, pirbuterol
class of all is beta-2 agonists
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9
Q

albuterol Trades?

A

Proventil HFA, Ventolin HFA, ProAir HFA

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10
Q

albuterol details?

A

beta-2 agonist
• Racemeic
• May have more side effects

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11
Q

levalbuterol Trade and details?

A

Xopenex HFA (quick relief, beta-2 agonist)
• R-isomer
• May have fewer side effects than albuterol

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12
Q

Xopenex generic?

A

levalbuterol

beta-2 agonist

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13
Q

Maxair generic and details?

A

pirbuterol (quick relief, beta-2 agonist)

Autohaler - breath activated MDI

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14
Q

pirbuterol Trade?

A

Maxair Autohaler

quick relief beta-2 agonist

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15
Q

long term control inhalers info?

A

beta-2 agonists (sympathomimetics)
• Indicated for asthma prophylaxis → will not relieve acute attack
• Dry powder inhalers
• BBW: increases risk of asthma related deaths in patients who use this alone instead of in combination with a steroid

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16
Q

long-term control Beta-2 generics?

A

salmeterol, indacaterol, formoterol

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17
Q

Serevent generic?

A

salmeterol

long acting beta-2 agonist

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18
Q

salmeterol Trade and details?

A
Serevent Diskus (long acting beta-2 agonist)
•	BID - DPI
•	Number on the top of the diskus means the number of doses remaining
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19
Q

Foradil generic?

A

formoterol

sympathomimetic - long acting

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20
Q

formoterol Trade and details?

A

Foradil Aerolizer (long acting b-2 agonist)
• BID - DPI
• Refrigerate in the pharmacy
• Can be kept at room temperature for 4 months by the patient

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21
Q

indacaterol Trade and details?

A
Arcapta NeoHaler (long acting b-2 agonist)
qday  --  DPI
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22
Q

Arcapta generic?

A

indacaterol

long acting b-2 agonist

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23
Q

anticholinergic bronchodilator details?

A

o Block cholinergic receptors in the lungs → blocks ACh → bronchodilation
o Indicated for asthma prophylaxis
o Side effect: xerostomia

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24
Q

anticholinergic bronchodilator generics?

A

ipratropium, tiotropium, aclidinium

ipratropium bromide + albuterol

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25
Q

ipratropium Trade and details?

A

Atrovent HFA (anticholinergic)
• QID
• MDI

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26
Q

tiotropium Trade and details?

A
Spiriva Handihaler (anticholinergic)
•	qday - long acting
•	DPI
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27
Q

aclidinium Trade and details?

A
Tudorza Pressair (anticholinergic)
•	BID - long acting
•	DPI
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28
Q

combination anticholinergic brochodilator generics?

A

albuterol, ipratropium bromide

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29
Q

combination bronchodilator Trade and details?

A

Combivent Respimat (albuterol, ipratropium bromide)
• MDI
• Rescue inhaler
• Contains soya lecithin; do not use if allergic to soy or peanuts

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30
Q

bronchodilators for nebulization details?

A

o Used in an updraft machine; drug diluted with normal saline
• Put solution for nebulization in machine → machine nebulizes liquid into a mist and patient breathes in with a mask for about 15 minutes

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31
Q

generics available for nebulization?

A

albuterol, levalbuterol, ipratropium, arformoterol, combo of albuterol and ipratropium

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32
Q

AccuNeb generic?

A

albuterol (nebulization)

QID

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33
Q

albuterol Trade for nebulization?

A

AccuNeb QID

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34
Q

Xopenex generic nebulization?

A

levalbuterol

QID

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35
Q

no Trade generic for nebulization?

A

ipratropium

QID

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36
Q

levalbuerol Trade for nebulization?

A

Xopenex solution for nebulization

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37
Q

arformoterol Trade?

A

Brovana

nebulization

38
Q

Brovana generic and details?

A
arformoterol for nebulization
•	BID
•	R-isomer of formoterol
•	Long-acting
•	Refrigerate in the pharmacy
39
Q

combination nebulization product Trade?

A

DuoNeb

40
Q

DuoNeb generic and details?

A

albuterol, ipratropium for nebulization

QID

41
Q

Inhaled corticosteroid details?

A

• Treat underlying cause of asthma by decreasing inflammation in the airways
• Indicated for asthma prophylaxis; will not relieve acute attack - Maintenance drugs
• Side effect: oral candidiasis
o Rinse mouth with water 15 minutes after using inhaler

42
Q

QVAR generic and details?

A

beclomethasone
inhaled corticosteroid
MDI - BID

43
Q

beclomethasone Trade?

A

QVAR

inhaled corticosteroid

44
Q

Flovent generic and details?

A

fluticasone
inhaled corticosteroid
MDI - BID

45
Q

budesonide Trade?

A

Pulmicort Flexhaler and Pulmicort Respules

46
Q

Pulmicort Flexhaler details?

A

budesonide - inhaled corticosteroid

BID - DPI

47
Q

Pulmicort Respules details?

A

budesonide - inhaled corticosteroid

BID - suspension for nebulization

48
Q

mometasone Trade?

A

Asmanex Twisthaler

inhaled corticosteroid

49
Q

Asmanex generic and details?

A

mometasone - inhaled corticosteroid
qday - DPI
• 4-11 years old: 110 mcg
• 12+ years old: 220 mcg

50
Q

ciclesonide Trade and details?

A

Alvesco - inhaled corticosteroid

MDI - BID

51
Q

Alvesco generic?

A

cclesonide - inhaled corticosteroid

52
Q

thrush details?

A

oral cadidiasis - candida albicans

53
Q

medications indicated for thrush?

A

gentian violet, nystatin, clotrimazole troches

54
Q

gentian violet details?

A
  • OTC

* Topical antiseptic - thrush

55
Q

nystatin details?

A
  • Rx only

* Antifungal- thrush

56
Q

clotrimazole details?

A
  • Rx only
  • Imidazole antifungal - thrush
  • Dissolve 1 troche in the mouth five times daily x 14 days
57
Q

combination bronchodilator/corticosteroid indication?

A

asthma prophylaxis

58
Q

Symbicort generic and details?

A

budesonide, formoterol
• Combination bronchodilator/corticosteroid
MDI - BID

59
Q

budesonide, formoterol Trade?

A

Symbicort

• Combination bronchodilator/corticosteroid

60
Q

Dulera generic and details?

A

mometasone, fomoterol
• Combination bronchodilator/corticosteroid
MDI - BID

61
Q

mometasone, formoterol Trade?

A

Dulera

• Combination bronchodilator/corticosteroid

62
Q

Advair generic and details?

A

fluticasone, salmeterol
• Combination bronchodilator/corticosteroid
BID

63
Q

fluticasone, salmeterol Trade?

A
Advair HFA (MDI - BID)
Advair Diskus (DPI - BID)
64
Q

inhaled antiviral agents details?

A
  • Indicated for treatment and prevention of the flu

* Neuraminidase inhibitors: neuraminidase is the enzyme that influenza needs to replicate

65
Q

antiviral agent generics?

A

oseltamivir and zanamivir

neuraminidase inhibitors

66
Q

zanamivir Trade and details?

A

Relenza Diskhaler
• 5 mg powder/blister - DPI
• Treatment: 10 mg BID x 5 days
• Prevention (household): 10 mg qday x 10 days
• Prevention (community): 10 mg qday x 28 days

67
Q

oseltamivir Trade and details?

A

Tamiflu - tablet

68
Q

Beconase generic?

A

beclomethasone

intranasal corticosteroid

69
Q

Nasacort generic?

A

triamcinolone

intranasal corticosteroid

70
Q

Rhinocort generic?

A

budesonide

intranasal corticosteroid

71
Q

no Trade intranasal corticosteroid?

A

flunisolide

72
Q

Flonase generic?

A

fluticasone propionate

intranasal corticosteroid

73
Q

Veramyst generic?

A

fluticasone furoate

intranasal corticosteroid

74
Q

Nasonex generic?

A

mometasone

intranasal corticosteroid

75
Q

Omnaris generic?

A

ciclesonide

intranasal corticosteroid

76
Q

beclomethasone Trade?

nasal

A

Beconase AQ

intranasal corticosteroid

77
Q

triamcinolone Trade?

A

Nasacort AQ

intranasal corticosteroid

78
Q

budesonide Trade?

nasal

A

Rhinocort Aqau

intranasal corticosteroid

79
Q

fluticasone Trades?

nasal

A

Flonase - propionate
Veramyst - furoate
intranasal corticosteroid

80
Q

mometasone Trade?

nasal

A

Nasonex

intranasal corticosteroid

81
Q

ciclesonide Trade (nasal)

A

Omnaris

intranasal corticosteroid

82
Q

intranasal mast cell stabilizer

A

Nasalcrom - cromolyn sodium

83
Q

intranasal pituitary hormone

A

DDAVP, Stimate - desmopressin acetate

84
Q

intranasal anticholinergic?

A

Atrovent Nasal Spray - ipratropium bromide

85
Q

intranasal antihistamine?

A

Astelin, Astepro - azelastine

86
Q

Combination intranasal?

A

Dymista - azelastine, fluticasone

87
Q

intranasal for osteoporosis?

A

Miacalcin - calcitonin

Fortical - calcitonin

88
Q

Leukotriene receptor antagonist indication:

A

inflammatory mediator

Ind: asthma prophylaxis

89
Q

Leukotriene receptor antagonists generics?

A

zafirlukast, montelukast, zileuton (kind of)

90
Q

zafirlukast Trade and details?

A

Accolate
o Leukotriene receptor antagonists
take on empty stomach

91
Q

montelukast Trade and details?

A

Singulair (leukotriene receptor antagonist)
• qday
• Indicated for prevention of exercise-induced asthma (2 hours prior), asthma prophylaxis, and allergic rhinitis
• 10 mg tablet: 15 and older
• 4 mg chewable tablet: 2-5 years old
• 5 mg chewable tablet: 6-14 years old
• 4 mg/packet granules: 6 months-5 years old; can sprinkle on food, but do not mix with liquid
• Can be taken without regard to meals

92
Q

zileuton Trade and details?

A

Zyflo CR
• Leukotriene formation inhibitor
• ER tablet
• BID