Inhalation agents Flashcards

1
Q

increases catecholamines

A

N20, Iso, Des

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2
Q

minimal change in minute ventilation/ resting CO2 levels

A

N20

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3
Q

Increases CMRO2

A

N20

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4
Q

Most potent trigger of MH?

A

Halothane

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5
Q

Does NOT decrease SVR?

A

Halothane

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6
Q

Blunts baroreceptor response

A

Halothane

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7
Q

Caution with EPI (causes arrythmias)

A

Halothane, Enflurane (4.5mg/kg), N20

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8
Q

Cerebral autoregulation blunted?

A

Halothane

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9
Q

increases cutaneous blood flow?

A

Halothane, isoflurane

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10
Q

Bronchodilator?

A

Halothane (potent), enflurane (

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11
Q

15-20% metabolized?

A

Halothane

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12
Q

Produces trifluroacetic acid?

A

Halothane, Isoflurane

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13
Q

Abolished hypoxic drive?

A

Enflurane

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14
Q

Marked respiratory depression at 1 MAC?

A

Enflurane

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15
Q

Increases secretion of CSF and resistance to CSF outflow?

A

Enflurane

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16
Q

2-5% metabolized?

A

Enflurane, Sevoflurane

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17
Q

MAINTAINS hepatic blood flow- dilates?

A

Isoflurane, Sevoflurane

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18
Q

0.2% metabolized?

A

Isoflurane

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19
Q

0.02% metabolized? (

A

Desflurane

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20
Q

What is the greatest producer of carbon monoxide?

A

Desflurane>enflurane, isoflurane> halothane, sevoflurane

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21
Q

What forms compound A?

A

Sevo, produces reactive thiol. use 2 L/min of FGF.

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22
Q

What causes coronary steal syndrome?

A

Isoflurane

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23
Q

Mild beta adrenergic stimulation?

A

Isoflurane

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24
Q

dilates coronary arteries?

A

Halothane, isoflurane

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25
Q

Enhances CSF reabsorption?

A

Isoflurane

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26
Q

Most irritating to airways?

A

Desflurane

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27
Q

Dose dependent decrease in response to TOF and tetanic PNS?

A

Desflurane

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28
Q

Only common agent that does not increase CVP?

A

Sevoflurane

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29
Q

Does NOT cause an SNS response with increase in concentration

A

Secoflurane

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30
Q

The most minimal airway irritation?

A

Sevoflurane

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31
Q

OK for inhalation induction?

A

Halothane and Sevoflurane

32
Q

Cerebral response to CO2 and auto regulation maintained at 1.5% depresses respirations?

A

Sevoflurane

33
Q

Avoid in renal failure?

A

Enflurane, Sevoflurane

34
Q

minimal change in minute ventilation/ resting CO2 levels

A

N20

35
Q

Increases CMRO2

A

N20

36
Q

Decreases hypoxic drive?

A

N2O, Halothane, Enflurane (abolished)

37
Q

Most potent trigger of MH?

A

Halothane

38
Q

Does NOT decrease SVR?

A

Halothane

39
Q

Blunts baroreceptor response

A

Halothane

40
Q

Caution with EPI (causes arrythmias)

A

Halothane, Enflurane (4.5mg/kg), N20

41
Q

Cerebral autoregulation blunted?

A

Halothane

42
Q

increases cutaneous blood flow?

A

Halothane, isoflurane

43
Q

Bronchodilator?

A

Halothane (potent), enflurane (

44
Q

Produces trifluroacetic acid?

A

Halothane, Isoflurane

45
Q

Abolished hypoxic drive?

A

Enflurane

46
Q

Marked respiratory depression at 1 MAC?

A

Enflurane

47
Q

Increases secretion of CSF and resistance to CSF outflow?

A

Enflurane

48
Q

Beneficial effects on hepatic oxygen delivery

A

Isoflurane, sevoflurane

49
Q

What is the greatest producer of carbon monoxide?

A

Desflurane>enflurane, isoflurane> halothane, sevoflurane

50
Q

What forms compound A?

A

Sevo, produces reactive thiol. use 2 L/min of FGF.

51
Q

What causes coronary steal syndrome?

A

Isoflurane

52
Q

Mild beta adrenergic stimulation?

A

Isoflurane

53
Q

dilates coronary arteries?

A

Halothane, isoflurane

54
Q

Silent EEG at 2 MAC?

A

Isoflurane

55
Q

Dose dependent decrease in response to TOF and tetanic PNS?

A

Desflurane

56
Q

Only common agent that does not increase CVP?

A

Sevoflurane

57
Q

Does NOT cause an SNS response with increase in concentration

A

Secoflurane

58
Q

The most minimal airway irritation?

A

Sevoflurane

59
Q

OK for inhalation induction?

A

Halothane and Sevoflurane

60
Q

Cerebral response to CO2 and auto regulation maintained at 1.5% depresses respirations?

A

Sevoflurane

61
Q

Avoid in renal failure?

A

Enflurane, Sevoflurane

62
Q

elderly/neonates see a decrease in HR

A

Isoflurane

63
Q

ICP is not increased at 1 MAC or less?

A

Isoflurane

64
Q

What 3 do not decrease CO?

A

Iso and Des, (sevo decreases a little)

65
Q

decreases BP by decreasing CO (vs decreasing SVR)

A

Halothane

66
Q

increases skeletal muscle flow by 4x

A

Isoflurane (also cutaneous blood flow like halothane)

67
Q

Does not decrease SVR?

A

Halothane and N2O

68
Q

Does not increase RR above 1 MAC

A

Isoflurane

69
Q

increases RR more than others at >1 mac

A

N2O

70
Q

does NOT increase CO2 levels!!!!

A

N2O

71
Q

CO maintained (does not decrease)

A

Des and Iso

72
Q

____ increases SNS, Map, HR, BP more than _____

A

Des increases SNS response more than ISO

73
Q

Increases MAC:

A

hypERthermia, hyperNAtremia, less than 1 Yr, red hair

74
Q

What decreases mac?

A

HypOthermia, acute alcohol, lithium, lidocain, hypotension (map

75
Q

does NOT affect MAC?

A

chronic alcohol, high O2/MAP, POTASSIUM up or down, thyroid issues.