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Pharm SS > Dosages > Flashcards

Dosages Flashcards

1
Q

Ranitidine/Zantac

A

50mg-100mg IV effective in 1 hour

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2
Q

Ondansetron/Zofran

A

4-8mg IV over 5 minutes

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3
Q

Sodium Citrate

A

30 mL of 0.3M PO 15-30 min before induction

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4
Q

Reglan/Metoclopramide

A

10-20 mg IV over 3-5 min 15 min before induction

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5
Q

Famotidine/Pepcid

A

20 mg IV over 2 min

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6
Q

Vecuronium:

A

Intubating dose = 0.1 mg/kg.
Maintenance dose = 0.01 -0.015mg/kg q 25-45 mins
Continuous infusion = 0.08-1.2mcg/kg/min

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7
Q

Rocuronium

A

intubation 0.6-1.2mg/kg
standard intubation dose = 0.6mg/kg
rapid sequence intubation dose = 1.2 mg/kg (good intubating conditions 2 min.)
Maintenance= 0.01 to 0.012 mg/kg/min

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8
Q

Mivacurium

A

Intubation= 0.2-0.25mg/kg

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9
Q

Cis-atricurium

A

Intubating dose = 0.1 - 0.2 mg/kg IV

Maintenance = 0.02mg/kg IV

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10
Q

Atracurium

A

0.4-0.5 mg/kg; then 0.08-0.1 mg/kg 15-45 minutes

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11
Q

Pancuronium

A

Intubation - 0.1 mg/kg

Maintenance – 0.01 mg/kg – 0.02 mg/kg Q20-60 min as needed

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12
Q

Succinylcholine

A

Laryngospasm dose: IV 10-20mg IV or 0.3mg/kg (CB)

IV intubation dose: 1-1.5mg/kg IV; onset 30- 90 seconds; E½t 2-4mins; clinical duration 8-15minutes

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13
Q

Atropine

A

Bradycardia: 0.4-1.0 mg IV.
0.01 mg/kg (with reversal agent) or 7-15mcg/kg
PEA, asystole: 1mg IV repeat every 3-5 minutes

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14
Q

Glycopyrrolate

A

0.01-0.02 mg/kg IV (reversal)
0.1-0.2 mg IV (antisialagogue)
0.2 mg for each 1.0 mg of neostigmine IV in same syringe
Bradycardial= 0.1 - 0.2 mg IV

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15
Q

Dexmedetomide/Precedex

A

1 mcg/kg bolus over 10-15 minutes; followed by 0.2 - 1 mcg/kg/hr infusion

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16
Q

Fentanyl

A

Premedication: IV– 25-100 mcg
Analgesia: 1-2 mcg/kg IV; 0.5-1mcg/kg Q 5 minutes

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17
Q

Remifentanil

A

Induction: 0.5-1mcg/kg over 60-90 seconds
Additional bolus: 0.1-1mcg/kg
Maintenance infusion with isoflurane or propofol = 0.05-2mcg/kg/min.

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18
Q

Sufentanil

A

Boluses of 0.1-1.0 mcg/kg
1-2 mcg/kg minor procedure balanced technique (i.e. other agents given)
2-8 mcg/kg for moderate procedures balanced technique (i.e. other agents given)
8-50 mcg/kg with 100% O2 with muscle relaxant produces anesthesia sole anesthetic
*note most of these ranges >2mcg/kg are not compatible with immediate post-op extubation!

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19
Q

Alfentanil

A

Analgesia: 5-30ug/kg followed by infusion of 0.4-1.7 mcg/kg/min
Induction: 50-200ug/kg

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20
Q

Morphine

A 
Between 2.5-15mg IV in divided doses (titrate 1-4 mg q5 minutes) q 3-4 hr.
Balanced anesthetic (with controlled ventilation) up to 2mg/kg
Continuous infusion: 0.8-10mg/hr (may increase to 80mg/hr with high opioid toleranc
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21
Q

Midazolam

A

Premedication or sedation: 0.5-5 mg IV/IM carefully titrated

Induction: 0.05-0.35 mg/kg IV (lower doses in premedicated patients)

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22
Q

Lorazepam

A

50mcg/kg not to exceed 4mg

IV: 1-4 mg

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23
Q

Diazepam

A

Pre-operative anxiolytic: IV: 2.5-10 mg, given in 0.5-2mg increments
PO: ­­­­­­5-15mg is recommended
Induction agent: 0.3-0.6 mg/kg IV

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24
Q

Meperidine

A

5mg q5 min (25mg-75 mg total)

12.5mg shivering 1gmax in 24hours

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25
Q

Hydromorphone

A

IV: 0.5-2 mg q 2-6 hrs

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26
Q

Ephedrine

A

5-25mg IV

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27
Q

Phenylephrine

A

50-200 mcg IV

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28
Q

Epinephrine

A

1-2 mcg/kg B2
4-5 mcg/kg B1
10-20 mcg/kg B and A

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29
Q

Norepinephrine

A

4-16 mcg/min

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30
Q

Esmolol

A

5-10mg IV q3min total of 80mg IV

31
Q

Dexamethasone

A

4-10mg IV given at the beginning of the anesthetic for PONV

32
Q

Diltiazem

A

For SVT: loading dose of 0.25 mg/kg over 2 minutes then infusion of 5-15 mg/hr

33
Q

Labetalol

A

5-20 mg q 5-10minutes up to 300mg total dose

34
Q

Propranolol

A

1-10mg; 1mg q 5min

resting heart rate of 55-60 bpm

35
Q

Metoprolol

A

1.25-5mg every 2-5min up to 15mg, with titration to HR and BP

36
Q

Neostigmine

A

0.05-0.07mg/kg with glyco (0.01 mg/kg)

37
Q

Dopamine

A

1-3mcg/kg/min D1
3-10mcg/kg/min B1
10mcg/kg/min alpha

38
Q

Dobutamine

A

2-10mcg/kg/min

39
Q

Diltiazem

A

SVT: loading dose 0.25mg bolus over 2 min then 5-15mg/hr

40
Q

Arginine Vasopressin

A

40 units IVP for CV arrest

20 units IV for varicies

41
Q

Hydralazine

A

2.5-20mg IV q4hrs or PRN in OR (peaks 15-20 mins)

42
Q

Nitroprusside

A

0.3-10mcg/kg/min

1-2mcg/kg/min for HTN crisis

43
Q

Nitroglycerin

A

IV: initial 5-10 mcg/min, titrate in range 5-200 mcg/min

44
Q

Phentolamine

A

1-5mg q 5 mins max 20mg IV bolus

45
Q

Albuterol

A

Bronchospasm: 4-8 puffs Q 20 minutes for 3 doses, then every 1-4 hours
Blunt airway response in asthmatic patients: 2- 4 puffs

46
Q

Furosemide

A

IV- 0.1 to 1.0 mg/kg

47
Q

Adenosine

A

SVT: 6mg, then 12 mg 60 seconds later

48
Q

Methylprednisolone

A

10-250mg IV q4-24 hour

49
Q

Hydrocortisone

A 
Minor: 25 mg IV
Moderate: 50-70
Major: 100mg - 150mg
Asthmatic bronchitis & severe asthma: 4 mg/kg IV bolus 
Anaphylaxis: 250 mg- 1.0 g IV
50
Q

Phenobarbitol

A

10-20 mg/kg IV, followed by 5 mg/kg q 15-30 min until seizure controlled or max. dose of 30mg/kg reached (status epilepticus and anticonvulsant)

51
Q

Ketorolac

A

30mg IV Q6 hours (daily max is 120mg)

52
Q

Isoproterenol

A

0.5-10mcg/min

53
Q

Phenoxybenzamine

A

10-120mg/day PO

54
Q

Scopolamine

A

0.3-0.6mg IV q4-6hrs

55
Q

Digoxin

A

0.5-1mg IV over 12-24 hours

56
Q

Ampicillin

A

2g IV 30 min preop

57
Q

Cefazolin

A

1-3 grams IV 30 min preop

58
Q

Gentamycin

A

60-120 mg IV

59
Q

Clindamycin

A

600mg IV preop

60
Q

Vancomycin

A

1 gm/250 ml NS over 60 minutes

61
Q

Metronidazole

A

500 mg over 10-20 mins

62
Q

Ciprofloxacin

A

200-400 mg IV over 60 mins

63
Q

Ketamine

A

Sedative: 0.2-0.5 mg/kg
Induction of general anesthesia: 0.5-2 mg/kg IV, 4-6 mg/kg IM
Maintenance: 1-2 mg/kg/hr

64
Q

Etomidate

A

intubation: 0.3-0.6 mg/kg
Maint: 10 mcg/kg/min with N2O and an opiate

65
Q

Propofol

A

1-2.5 mg/kg for induction
25-100 mcg/kg/min for sedation
100-300 mcg/kg/min for maint.

66
Q

Flumazenil

A

0.2 mg IV, wait 2 min, then 0.1mg q 60 sec, max 3 mg

67
Q

Naloxone

A

0.1-2 mg IV q 2-3 min titrate slowly

68
Q

Ketorolac

A

30-60 mg, then 15-30 mg every 6 hrs; max daily dose 120 mg

69
Q

Regular Insulin

A

1unit of regular insulin can be expected to decrease BS 30-50 mg/dL
Maintenance infusion – 0.05-0.1 units/kg/hr titrated
(check BS every hour with a continuous infusion and every 30 minutes after an infusion rate change).

70
Q

Amiodarone

A

Stable VT/SVT: load with 150 mg IV over 10 minutes, 6 hours (1mg/min), and 18 hours (0.5mg/min)
Pulseless VT/VF: 300 mg IVP
If VT/VF recurs, 150 mg IVP followed by drip (1 mg/min for 6 hours then 0.5 mg/min for 18 hours)

71
Q

Glucagon

A

To increase SV and HR independent of adrenergic receptors:
1-5mg IV over 5minutes/ continuous infusion of 20mg/hr

Diagnostic aid for GI procedures: 0.25-2 mg IV
SOO spasm: 0.3mg IV

72
Q

Hydralazine

A

2.5-10mg IV q 10-20 min

73
Q

Labetalol

A

5-20mg q10 min (E1/2T 5-8 hrs)

74
Q

Nitroprusside

A

0.5-10mcg/kg/min

Pharm SS (12 decks)

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