Dosages

Question 1

Ranitidine/Zantac

Answer 1

50mg-100mg IV effective in 1 hour

Question 2

Ondansetron/Zofran

Answer 2

4-8mg IV over 5 minutes

Question 3

Sodium Citrate

Answer 3

30 mL of 0.3M PO 15-30 min before induction

Question 4

Reglan/Metoclopramide

Answer 4

10-20 mg IV over 3-5 min 15 min before induction

Question 5

Famotidine/Pepcid

Answer 5

20 mg IV over 2 min

Question 6

Vecuronium:

Answer 6

Intubating dose = 0.1 mg/kg.
Maintenance dose = 0.01 -0.015mg/kg q 25-45 mins
Continuous infusion = 0.08-1.2mcg/kg/min

Question 7

Rocuronium

Answer 7

intubation 0.6-1.2mg/kg
standard intubation dose = 0.6mg/kg
rapid sequence intubation dose = 1.2 mg/kg (good intubating conditions 2 min.)
Maintenance= 0.01 to 0.012 mg/kg/min

Question 8

Mivacurium

Answer 8

Intubation= 0.2-0.25mg/kg

Question 9

Cis-atricurium

Answer 9

Intubating dose = 0.1 - 0.2 mg/kg IV

Maintenance = 0.02mg/kg IV

Question 10

Atracurium

Answer 10

0.4-0.5 mg/kg; then 0.08-0.1 mg/kg 15-45 minutes

Question 11

Pancuronium

Answer 11

Intubation - 0.1 mg/kg

Maintenance – 0.01 mg/kg – 0.02 mg/kg Q20-60 min as needed

Question 12

Succinylcholine

Answer 12

Laryngospasm dose: IV 10-20mg IV or 0.3mg/kg (CB)

IV intubation dose: 1-1.5mg/kg IV; onset 30- 90 seconds; E½t 2-4mins; clinical duration 8-15minutes

Question 13

Atropine

Answer 13

Bradycardia: 0.4-1.0 mg IV.
0.01 mg/kg (with reversal agent) or 7-15mcg/kg
PEA, asystole: 1mg IV repeat every 3-5 minutes

Question 14

Glycopyrrolate

Answer 14

0.01-0.02 mg/kg IV (reversal)
0.1-0.2 mg IV (antisialagogue)
0.2 mg for each 1.0 mg of neostigmine IV in same syringe
Bradycardial= 0.1 - 0.2 mg IV

Question 15

Dexmedetomide/Precedex

Answer 15

1 mcg/kg bolus over 10-15 minutes; followed by 0.2 - 1 mcg/kg/hr infusion

Question 16

Fentanyl

Answer 16

Premedication: IV– 25-100 mcg
Analgesia: 1-2 mcg/kg IV; 0.5-1mcg/kg Q 5 minutes

Question 17

Remifentanil

Answer 17

Induction: 0.5-1mcg/kg over 60-90 seconds
Additional bolus: 0.1-1mcg/kg
Maintenance infusion with isoflurane or propofol = 0.05-2mcg/kg/min.

Question 18

Sufentanil

Answer 18

Boluses of 0.1-1.0 mcg/kg
1-2 mcg/kg minor procedure balanced technique (i.e. other agents given)
2-8 mcg/kg for moderate procedures balanced technique (i.e. other agents given)
8-50 mcg/kg with 100% O2 with muscle relaxant produces anesthesia sole anesthetic
*note most of these ranges >2mcg/kg are not compatible with immediate post-op extubation!

Question 19

Alfentanil

Answer 19

Analgesia: 5-30ug/kg followed by infusion of 0.4-1.7 mcg/kg/min
Induction: 50-200ug/kg

Question 20

Morphine

Answer 20

Between 2.5-15mg IV in divided doses (titrate 1-4 mg q5 minutes) q 3-4 hr.
Balanced anesthetic (with controlled ventilation) up to 2mg/kg
Continuous infusion: 0.8-10mg/hr (may increase to 80mg/hr with high opioid toleranc

Question 21

Midazolam

Answer 21

Premedication or sedation: 0.5-5 mg IV/IM carefully titrated

Induction: 0.05-0.35 mg/kg IV (lower doses in premedicated patients)

Question 22

Lorazepam

Answer 22

50mcg/kg not to exceed 4mg

IV: 1-4 mg

Question 23

Diazepam

Answer 23

Pre-operative anxiolytic: IV: 2.5-10 mg, given in 0.5-2mg increments
PO: ­­­­­­5-15mg is recommended
Induction agent: 0.3-0.6 mg/kg IV

Question 24

Meperidine

Answer 24

5mg q5 min (25mg-75 mg total)

12.5mg shivering 1gmax in 24hours

Question 25

Hydromorphone

Answer 25

IV: 0.5-2 mg q 2-6 hrs

Question 26

Ephedrine

Answer 26

5-25mg IV

Question 27

Phenylephrine

Answer 27

50-200 mcg IV

Question 28

Epinephrine

Answer 28

1-2 mcg/kg B2 4-5 mcg/kg B1 10-20 mcg/kg B and A

Question 29

Norepinephrine

Answer 29

4-16 mcg/min

Question 30

Esmolol

Answer 30

5-10mg IV q3min total of 80mg IV

Question 31

Dexamethasone

Answer 31

4-10mg IV given at the beginning of the anesthetic for PONV

Question 32

Diltiazem

Answer 32

For SVT: loading dose of 0.25 mg/kg over 2 minutes then infusion of 5-15 mg/hr

Question 33

Labetalol

Answer 33

5-20 mg q 5-10minutes up to 300mg total dose

Question 34

Propranolol

Answer 34

1-10mg; 1mg q 5min | resting heart rate of 55-60 bpm

Question 35

Metoprolol

Answer 35

1.25-5mg every 2-5min up to 15mg, with titration to HR and BP

Question 36

Neostigmine

Answer 36

0.05-0.07mg/kg with glyco (0.01 mg/kg)

Question 37

Dopamine

Answer 37

1-3mcg/kg/min D1 3-10mcg/kg/min B1 10mcg/kg/min alpha

Question 38

Dobutamine

Answer 38

2-10mcg/kg/min

Question 39

Diltiazem

Answer 39

SVT: loading dose 0.25mg bolus over 2 min then 5-15mg/hr

Question 40

Arginine Vasopressin

Answer 40

40 units IVP for CV arrest | 20 units IV for varicies

Question 41

Hydralazine

Answer 41

2.5-20mg IV q4hrs or PRN in OR (peaks 15-20 mins)

Question 42

Nitroprusside

Answer 42

0.3-10mcg/kg/min | 1-2mcg/kg/min for HTN crisis

Question 43

Nitroglycerin

Answer 43

IV: initial 5-10 mcg/min, titrate in range 5-200 mcg/min

Question 44

Phentolamine

Answer 44

1-5mg q 5 mins max 20mg IV bolus

Question 45

Albuterol

Answer 45

Bronchospasm: 4-8 puffs Q 20 minutes for 3 doses, then every 1-4 hours Blunt airway response in asthmatic patients: 2- 4 puffs

Question 46

Furosemide

Answer 46

IV- 0.1 to 1.0 mg/kg

Question 47

Adenosine

Answer 47

SVT: 6mg, then 12 mg 60 seconds later

Question 48

Methylprednisolone

Answer 48

10-250mg IV q4-24 hour

Question 49

Hydrocortisone

Answer 49

``` Minor: 25 mg IV Moderate: 50-70 Major: 100mg - 150mg Asthmatic bronchitis & severe asthma: 4 mg/kg IV bolus Anaphylaxis: 250 mg- 1.0 g IV ```

Question 50

Phenobarbitol

Answer 50

10-20 mg/kg IV, followed by 5 mg/kg q 15-30 min until seizure controlled or max. dose of 30mg/kg reached (status epilepticus and anticonvulsant)

Question 51

Ketorolac

Answer 51

30mg IV Q6 hours (daily max is 120mg)

Question 52

Isoproterenol

Answer 52

0.5-10mcg/min

Question 53

Phenoxybenzamine

Answer 53

10-120mg/day PO

Question 54

Scopolamine

Answer 54

0.3-0.6mg IV q4-6hrs

Question 55

Digoxin

Answer 55

0.5-1mg IV over 12-24 hours

Question 56

Ampicillin

Answer 56

2g IV 30 min preop

Question 57

Cefazolin

Answer 57

1-3 grams IV 30 min preop

Question 58

Gentamycin

Answer 58

60-120 mg IV

Question 59

Clindamycin

Answer 59

600mg IV preop

Question 60

Vancomycin

Answer 60

1 gm/250 ml NS over 60 minutes

Question 61

Metronidazole

Answer 61

500 mg over 10-20 mins

Question 62

Ciprofloxacin

Answer 62

200-400 mg IV over 60 mins

Question 63

Ketamine

Answer 63

Sedative: 0.2-0.5 mg/kg Induction of general anesthesia: 0.5-2 mg/kg IV, 4-6 mg/kg IM Maintenance: 1-2 mg/kg/hr

Question 64

Etomidate

Answer 64

intubation: 0.3-0.6 mg/kg Maint: 10 mcg/kg/min with N2O and an opiate

Question 65

Propofol

Answer 65

1-2.5 mg/kg for induction 25-100 mcg/kg/min for sedation 100-300 mcg/kg/min for maint.

Question 66

Flumazenil

Answer 66

0.2 mg IV, wait 2 min, then 0.1mg q 60 sec, max 3 mg

Question 67

Naloxone

Answer 67

0.1-2 mg IV q 2-3 min titrate slowly

Question 68

Ketorolac

Answer 68

30-60 mg, then 15-30 mg every 6 hrs; max daily dose 120 mg

Question 69

Regular Insulin

Answer 69

1unit of regular insulin can be expected to decrease BS 30-50 mg/dL Maintenance infusion – 0.05-0.1 units/kg/hr titrated (check BS every hour with a continuous infusion and every 30 minutes after an infusion rate change).

Question 70

Amiodarone

Answer 70

Stable VT/SVT: load with 150 mg IV over 10 minutes, 6 hours (1mg/min), and 18 hours (0.5mg/min) Pulseless VT/VF: 300 mg IVP If VT/VF recurs, 150 mg IVP followed by drip (1 mg/min for 6 hours then 0.5 mg/min for 18 hours)

Question 71

Glucagon

Answer 71

To increase SV and HR independent of adrenergic receptors: 1-5mg IV over 5minutes/ continuous infusion of 20mg/hr Diagnostic aid for GI procedures: 0.25-2 mg IV SOO spasm: 0.3mg IV

Question 72

Hydralazine

Answer 72

2.5-10mg IV q 10-20 min

Question 73

Labetalol

Answer 73

5-20mg q10 min (E1/2T 5-8 hrs)

Question 74

Nitroprusside

Answer 74

0.5-10mcg/kg/min