Info From Practice Problems

Question 1

Which receptor in RBC helps remove complement from circulation

Answer 1

CR1

Question 2

Factor B is used in which pathway

Answer 2

Alt. Pathway

Question 3

What does Factor H do

Answer 3

Regulates C3b

Question 4

What is CD95

Answer 4

FAS

Question 5

How does Herpes and EBV evade immue system

Answer 5

Inhibition of Ag presentation

Question 6

What are the two cytokines required for memory T-cell survival

Answer 6

IL-7 and IL-15

Question 7

Define Type I hypersensitivity

Answer 7

Immediate

Uses IgE, Th2 cells, mast cells, and Eos

Aka allergies

Question 8

Define Type II hypersensitivity

Answer 8

Uses IgM and IgG against cell surfaces

This means opos, Complement and FC mediated activation fo Leukocytes ALL ACTIVATED BY IgM OR IgG

Question 9

Define Type III hypersensitivity

Answer 9

Immune complexes of circulating Ag deposited in blood stream

Causes inflammation in the blood supply

Question 10

Define Type IV reaction

Answer 10

Late-term reaction

Involves T-cells that activate either macrophages and inflammation or direct cell lysis

This reaction attacks the cells themselves and the organs in general

Question 11

Define serum sickness

Answer 11

Inducers by systemic administration of a protein Ag which illicit an Ab response and leads to the circulation of immune complexes

Example: systemic lupus erthematosus

Question 12

Define arthus reaction

Answer 12

A localized immune complex rx. Induced by sub q ad min of protein Ag to a previously immunized specimen which results in the formation of immune complexes at the site of the Ag injection and local vasculitis