Inflmmatory non Inflammatory Rheum Dis Flashcards
What is the primary cause of inflammatory rheumatologic diseases?
Immune system activation.
Which inflammatory marker is decreased during inflammation?
Albumin.
What are the extra-articular manifestations of inflammatory rheumatic diseases?
Systemic symptoms like fatigue, fever, weight loss, and organ involvement.
What antibodies are commonly positive in rheumatoid arthritis?
Rheumatoid factor (RF) and anti-CCP.
What imaging finding is characteristic of rheumatoid arthritis?
Joint erosions.
What type of therapy is typically used to treat rheumatoid arthritis?
DMARDs and biologics.
Which systemic disease presents with serositis
such as pleuritis and pericarditis?
What neurological symptoms may occur in Systemic Lupus Erythematosus (SLE)?
Seizures and psychosis.
What are common features of spondyloarthritis?
Inflammatory back pain, sacroiliitis, enthesitis, dactylitis.
What symptom distinguishes inflammatory back pain from mechanical back pain?
Morning stiffness lasting more than 30 minutes.
What is the gender distribution of psoriatic arthritis?
Affects males and females equally.
What skin features are associated with psoriatic arthritis?
Nail changes, scalp psoriasis, and inverse psoriasis.
What vascular condition is characterized by unexplained fever and multiorgan ischemia?
Vasculitis.
What are the typical symptoms of vasculitis-related peripheral nerve involvement?
Numbness, tingling, and asymmetric polyneuropathy.
What distinguishes non-inflammatory joint diseases from inflammatory ones?
Lack of swelling, warmth, and systemic symptoms.
What is the underlying cause of osteoarthritis?
Degenerative joint disease due to wear and tear.
What is a hallmark physical finding in osteoarthritis?
Crepitus (crackling sound) during joint movement.
What causes the pain and tenderness in fibromyalgia?
Abnormal pain signal processing in the nervous system.
What is the primary diagnostic marker for fibromyalgia?
There is no specific lab marker; diagnosis is clinical.
What is the characteristic feature of inflammatory markers in non-inflammatory diseases?
Normal CRP and ESR levels.
