Inflammatory Vascular Disorders Flashcards
PAN
Often you will also see lobular fat necrosis
If you see mixed vasculitis of small and medium sized viessels with endothelial “dirty” necrosis and neutrophils what should you think of
Septic vasculitis
Granuloma Faciale
Grenz zone. Misonomer as not true granuloma. Mixture of lymphocytes, neutrophils, eos, histiocytes all evenly mingled together filling up the dermis. (No microabscesses as you would see in an infectious process).
Erythema Elevatum Diutinum
LCV plus onion skin fibrosis
Sweet syndrome
Neutrophilic dermatosis with papillary dermal edema
EAC
Superficial gyrate erythema category
This DDX also includes Erythema Marginatum
Tumid Lupus
Superficial and Deep Perivascular lymphocytic inflammation
Dermal Mucin
Lymphocytes in Eccrine Coils
No epidermal interface change or follicular plugging as seen in DLE
*This is histologically indistinguishable from Reticular Erythematous Mucinosis
Polymorphous Light Eruption
Papillary Dermal Edema
Superficial and Deep Perivascular Inflammation
+/- Spongiosis
Malignant Atrophic Papulosis
aka Degos Disease
Red papules that develop ivory white atrophic centers
Bowel perforation and stroke
Wedge shaped superficial and deep perivascular lymphoid infiltrate with vascular damage
Over time you will get atrophy of the epidermis, dermal mucinosis, and avascular necrosis of dermal structures
Insect bite
Papillary Dermal Edema
Wedge Shaped Superficial and Deep Perivascular Lymphoid Infiltrate
Lots of Eos
Epidermal Necrosis sometimes
Pernio
Acral site
Fluffy papillary dermal edema
Superficial and deep perivascular lymphoid infiltrate right down to eccrine coils
*No mucin
Mimicker most commonly is PMLE but the acral site here is important
Type I cryo
This is a manifestation of plasma cell dyscrasia. Vessels Occluded by pink jelly substance
Perifollicular purpura
Scurvy
