Inflammatory Response Flashcards
What are the cells of the non specific response?
Phagocytic cells
Non phagocytic cells
What are the 4 non specific innate defenses?
Structural barriers
White blood cells
Antimicrobial proteins
Inflammatory response
What characterises the non specific response?
Innate
Against anything foreign
Always the same
What are two examples of non specific response?
Inflammatory response
Acute phase response
What are the signs of acute inflammation?
Redness
Heat
Swelling
Pain
What does acute inflammation involve?
Dilation of small blood vessels
Increased blood flow
Increased permeability
Cell recruitment and migration
What are the mediators of the immune response?
Vasoactive amines
Arachidonic acid metabolites
Complement and other systems
Cytokines
What is the complement system?
A series of proteins in plasma
How can the complement system be activated?
Classical pathway
Alternate pathway
What are the products of the complement system?
Opsonins
Anaphylatoxins
Chemotactic factors
Attack complexes
What are the functions of cytokines?
Chemo taxis
Cellular proliferation
What are the stages of cell recruitment?
Margination Adhesion Migration Chemotaxis Phagocytosis
What is the acute phase response?
A whole body response to infection
What does the acute phase response cause?
Increased number of neutrophils
greater production of acute phase proteins
What is an immunogen?
Stimulates a specific immune response