Inflammatory response Flashcards
e body’s specific protective response to an
invading foreign agent or organism
IMMUNITY
Refers to the study of diseases resulting from
dysfunctions within the immune system.
IMMUNOPATHOLOGY
Normal protective immune response paradoxically
turns against or attacks the body, leading to tissue
damage.
AUTOIMMUNITY
produces inappropriate or exaggerated
responses to specific antigens
HYPERSENSITIVITY
Immunoglobulins are overproduced.
GAMMOPATHIES
begins
with the B lymphocytes, which can transform
themselves into plasma cel
HUMORAL IMMUNE RESPONSE
also involves the T lymphocytes, which can turn into
special cytotoxic (or killer) T cells
CELLULAR IMMUNE RESPONSE
also called antibody-mediated immunity
● based on antibody activity
HUMORAL IMMUNITY
ased on action of Plasma cell specific kinds of T
lymphocytes
CELLULAR IMMUNITY
e B lymphocytes, or B cells, produce antibodies.
e B lymphocytes, or B cells, produce antibodies.
rge proteins called immunoglobulins
because they are found in the globulin fraction of the
plasma proteins
Antibodies a
ppears in serum and tissues (interstitial fluid)
o Assumes a major role in bloodborne and tissue
infections
IgG (75% of Total Immunoglobulin)
Appears in body fluids (blood, saliva, tears,
breast milk, and pulmonary, gastrointestinal,
prostatic, and vaginal secretions
IgA (15% of Total Immunoglobulin)
Appears mostly in intravascular serum
o Appears as the first immunoglobulin produced in
response to bacterial and viral infections
IgM (10% of Total Immunoglobulin
Possibly influences B-lymphocyte differentiation,
but role is unclear
IgD (0.2% of Total Immunoglobulin)
Takes part in allergic and some hypersensitivity
reactions
o Combats parasitic infections
IgE (0.004% of Total Immunoglobulin)
activated upon recognition of antigens and
stimulate the rest of the immune system.
HELPER T CELLS
attack the antigen directly by altering the cell
membrane and causing cell lysis (
CYTOTOXIC T CELLS (KILLER T CELLS)
e ability to decrease B-cell production, thereby
keeping the immune response at a level that is
compatible with health
SUPPRESSOR T CELL
responsible for recognizing antigens from
previous exposure and mounting an immune
response.
MEMORY T CELLS
substance that elicits an immune
response
ANTIGENS
