Inflammatory Myopathies Flashcards

1
Q

what are the two types of inflammatory myopathies that we learned

A

polymyositis

dermatomyositis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

what are the general features of inflammatory myopathies

A

progresive and SYMMETRIC muscle weakness
PROXIMAL muscle weakness
facial muscles unaffected
can have dysphagia or head drop

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

where does the weakness start in polymyositis

A

in legs

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

how long does it take for polymyositis to progress

A

weeks to months

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

what happens to the CK levels in polymyositis

A

elevated

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

what is dermatomyositis

A

characteristic rash with accompanying muscle weakness

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

what is heliotropic hue

A

blue/purple discoloration of the upper lids with edema

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

what is gottron’s sign

A

flat red rash on the face, upper trunk, and erythema of the knuckles with a raised violaceous scaley eruption

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

what is the V sign

A

erythematous rash on the neck and anterior chest, worse after sun exposure

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

what can accompany dermatomyositis (overlap)

A

with scleroderma and mixed connective tissue disease

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

what do the white blood cells do in inflammatory myopathies

A

invade muscles

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

what are the labs like for inflammatory myopathies

A

elevated CK
+Jo antibody (SPECIFIC MYOSITIS ANTIBODY)
EMG-
MRI of the affected muscle shows inflammation
muscle biopsy is the confirmation + inflammation (lymphocytes invading the muscle fibers)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

what is the treatment for inflamm myopathies

A

corticosteriods
other immunosuppressive agents if patient fails 3 month steriod trial
Immunomodulation: IVIg
PT

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

what happens to the CK when the muscle strength improves

A

the CK decreases

How well did you know this?
1
Not at all
2
3
4
5
Perfectly