Inflammatory Joint Disorders Flashcards

1
Q

What are the 4 Key characteristics of Inflammatory joint disorders?

A
  • -Symmetric erosions
  • -Soft tissue swelling
  • -Uniform loss of joint space
  • -Juxta-articular osteoporosis (bare area)
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2
Q

What are the 2 types of inflammatory diseases?

A

Seropositive (Rheumatoid types)

Seronegative (Rheumatoid variants)

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3
Q

What are the 4 types of Seropositive inflammatory diseases?

A
  • -RA
  • -SLE
  • -Scleroderma
  • -Jaccoud’s
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4
Q

What are the 4 types of Seronegative inflammatory diseases?

A
  • -AS
  • -Reactive
  • -Psoriatic arthritis
  • -Enteropathic arthritis
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5
Q

What are 2 characteristics of Rheumatoid arthritis?

A
  • -Pannus forming

- -Bilateral symmetric

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6
Q

Rheumatoid arthritis targets what 3 sites?

A
  • -Hands
  • -Feet
  • -Cervical spine
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7
Q

What symptoms differentiate RA in the hand from other arthritides?

A

Pain, tenderness, swelling, stiffness ESPECIALLY IN AM

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8
Q

What 2 joints are most commonly affected by RA in the hand?

A

PIPs and MCPs

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9
Q

Boutonnière deformity affects what joints and how?

A
  • -DIP extension

- -PIP flexion

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10
Q

Swan neck deformity affects what joints and how?

A
  • -DIP flexion

- -PIP extension

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11
Q

Haygarth’s nodes affect what joints and how?

A

Soft tissue swelling adjacent to MCP

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12
Q

What is the first sign of RA in the wrist?

A

Soft tissue swelling at the distal ulna

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13
Q

If untreated, RA in the wrist will lead to erosions at what locations?

A
  • -Distal ulna

- -Radial styloid

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14
Q

How does RA affect the knees?

A

Symmetric loss of joint space (both medial and lateral)

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15
Q

How does RA affect the hips?

A

Bilateral symmetric decrease in joint space

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16
Q

If a patient has RA in the cervical spine, what must you evaluate?

A

Upper C-spine stability (ADI space)

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17
Q

How is Juvenile RA different from adult RA?

A

Juvenile = Seronegative

Adult = Seropositive

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18
Q

Juvenile RA produces what growth deformity?

A

Ballooned epiphyses

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19
Q

What are the target sites of Juvenile RA?

A
  • -Knees
  • -Ankles
  • -Hands
  • -Hips
  • -Cervical spine
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20
Q

How does SLE differ from RA or OA?

A

Reversible deformities:

  • -Ulnar drift
  • -Swan-neck/boutonnière
  • -hitchhiker thumb
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21
Q

How is Jaccoud’s arthropathy different from RA or OA?

A

Non-erosive, reversible joint deformity

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22
Q

What hand and feet deformities are associated w/ the Jaccoud’s arthropathy?

A

–Ulnar deviations and flexion of the MCPs

–Fibular deviation of the MTPs

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23
Q

What seropositive arthropathy begins w/ GI symptoms, Raynaud’s phenomena and RA-like arthritis?

A

Scleroderma

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24
Q

What population is most at risk for Scleroderma?

A

Women, onset is 30-50

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25
What seropositive arthropathy doesn't have spinal involvement?
Scleroderma
26
What are the 2 distinctive findings that would lead some be diagnosed w/ scleroderma?
Mouse-like facies and hidebound skin
27
What is Crest Syndrome?
- -Calcinosis - -Raynaud's phenomenon - -Esophageal dysmotility - -Sclerodactyly - -Telangiectasia
28
CREST Syndrome is associated w/ what arthropathy?
Scleroderma
29
What seropositive arthropathy has retraction of the fingertips w/ resorption of the distal tufts?
Scleroderma
30
What is Acro osteolysis?
Resorption of the distal bony phalanges
31
What is the lab finding for seronegative arthropathies?
POSITIVE HLA-B27
32
What are the 4 Seronegative RA variants?
- -Psoriatic arthritis - -Enteropathic arthritis - -AS - -Reactive
33
What is the most common seronegative RA variant?
AS
34
AS is a chronic inflammatory condition most commonly affecting what populations?
Males
35
Ankylosing Spondylitis is 100% involved in what joint?
SI joint
36
How is Ankylosing Spondylitis differentiated from the other arthropathies affecting the SI joints?
Bilateral symmetric
37
Ankylosing Spondylitis erosions present as what sign?
Rosary bead sign
38
Ankylosing Spondylitis involving the upper SI will present with what sign?
Star sign
39
How does AS affect the vertebral body?
- -destroy corner of vertebral body - -squaring of vertebrae anteriorly - -ossification of outer annular fibers
40
What seronegative RA variant presents as "bamboo spine?"
AS
41
What seronegative RA variant presents as "Shiny corner sign?"
AS
42
What is the difference between marginal and non-marginal?
Marginal = originates at vertebral margin Non-marginal = originates mid-body
43
What is a syndesmophyte?
Bony growth originating inside a ligament
44
Radiographically what is the difference between marginal and non-marginal?
Marginal = thin Non-marginal = thick
45
What are 3 signs of AS at the apophyseal joints?
Erosion, sclerosis, loss of space
46
If AS produces a "Trolly track sign," what 4 ligaments will ossify?
- -Capsule, - -Ligamentum Flavum - -Inter/supraspinous lig
47
If AS produces a "Dagger sign," what 2 ligaments will ossify?
Inter/supraspinous ligaments
48
What 3 joints are affected w/ psoriatic arthritis?
- -Peripheral joints - -SI - -Spine
49
If you find arthritis affecting peripheral joints, SI, spine, and the patient has nail pitting what is the pathology?
Psoriatic Arthritis
50
What joints in the hand are affected by psoriatic arthritis?
DIPs and PIPs
51
What is it called if psoriatic arthritis 3 joints in the hand?
Ray pattern
52
What type of pattern does psoriatic arthritis present as in the hands?
Asymmetric, joint widening, and erosion
53
What do the marginal erosions of the psoriatic arthritis resemble?
Mouse ears
54
What form of arthritis presents with: - -Conjuctivitis - -Urethritis - -Heel spur or retrocalcaneal bursitis
Reactive arthritis
55
How does one distinguish the reactive arthritis from psoriatic arthritis?
Reactive primarily involves feet, psoriatic arthritis primarily involves hands
56
What is the foot rash associated w/ reactive arthritis?
Keratoma blennorrhagica
57
What are the 4 common sites involving CPPD?
- -Knee (menisci) - -Wrist - -MCPs - -Symphysis pubis
58
What is the most frequent joint for clinical and radiographic changes of CPPD?
Knee (menisci)
59
If CPPD is in the wrist, it will present as a calcification of triangular cartilage in what joint?
Ulnar meniscial triquetral joint
60
Hemochromatosis presents as a triad of what 3 things?
- -cirrhosis - -diabetes - -bronze colored skin
61
What radiographic sign will hemochromatosis present with in the hand?
MCP hook osteophytes
62
What pathology presents w/ an "overhanging edge/margin" sign, at periarticular erosions?
Gout
63
What 3 lab tests are used to determine seropositive/RA types?
Increased ESR, + ANA test, --HLA-B27
64
What 3 lab tests are used to determine seronegative/RA variants?
Increased ESR, -- ANA test, + HLA-B27