Inflammatory Joint Disorders Flashcards

1
Q

What are the 4 Key characteristics of Inflammatory joint disorders?

A
  • -Symmetric erosions
  • -Soft tissue swelling
  • -Uniform loss of joint space
  • -Juxta-articular osteoporosis (bare area)
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2
Q

What are the 2 types of inflammatory diseases?

A

Seropositive (Rheumatoid types)

Seronegative (Rheumatoid variants)

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3
Q

What are the 4 types of Seropositive inflammatory diseases?

A
  • -RA
  • -SLE
  • -Scleroderma
  • -Jaccoud’s
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4
Q

What are the 4 types of Seronegative inflammatory diseases?

A
  • -AS
  • -Reactive
  • -Psoriatic arthritis
  • -Enteropathic arthritis
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5
Q

What are 2 characteristics of Rheumatoid arthritis?

A
  • -Pannus forming

- -Bilateral symmetric

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6
Q

Rheumatoid arthritis targets what 3 sites?

A
  • -Hands
  • -Feet
  • -Cervical spine
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7
Q

What symptoms differentiate RA in the hand from other arthritides?

A

Pain, tenderness, swelling, stiffness ESPECIALLY IN AM

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8
Q

What 2 joints are most commonly affected by RA in the hand?

A

PIPs and MCPs

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9
Q

Boutonnière deformity affects what joints and how?

A
  • -DIP extension

- -PIP flexion

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10
Q

Swan neck deformity affects what joints and how?

A
  • -DIP flexion

- -PIP extension

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11
Q

Haygarth’s nodes affect what joints and how?

A

Soft tissue swelling adjacent to MCP

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12
Q

What is the first sign of RA in the wrist?

A

Soft tissue swelling at the distal ulna

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13
Q

If untreated, RA in the wrist will lead to erosions at what locations?

A
  • -Distal ulna

- -Radial styloid

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14
Q

How does RA affect the knees?

A

Symmetric loss of joint space (both medial and lateral)

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15
Q

How does RA affect the hips?

A

Bilateral symmetric decrease in joint space

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16
Q

If a patient has RA in the cervical spine, what must you evaluate?

A

Upper C-spine stability (ADI space)

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17
Q

How is Juvenile RA different from adult RA?

A

Juvenile = Seronegative

Adult = Seropositive

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18
Q

Juvenile RA produces what growth deformity?

A

Ballooned epiphyses

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19
Q

What are the target sites of Juvenile RA?

A
  • -Knees
  • -Ankles
  • -Hands
  • -Hips
  • -Cervical spine
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20
Q

How does SLE differ from RA or OA?

A

Reversible deformities:

  • -Ulnar drift
  • -Swan-neck/boutonnière
  • -hitchhiker thumb
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21
Q

How is Jaccoud’s arthropathy different from RA or OA?

A

Non-erosive, reversible joint deformity

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22
Q

What hand and feet deformities are associated w/ the Jaccoud’s arthropathy?

A

–Ulnar deviations and flexion of the MCPs

–Fibular deviation of the MTPs

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23
Q

What seropositive arthropathy begins w/ GI symptoms, Raynaud’s phenomena and RA-like arthritis?

A

Scleroderma

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24
Q

What population is most at risk for Scleroderma?

A

Women, onset is 30-50

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25
Q

What seropositive arthropathy doesn’t have spinal involvement?

A

Scleroderma

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26
Q

What are the 2 distinctive findings that would lead some be diagnosed w/ scleroderma?

A

Mouse-like facies and hidebound skin

27
Q

What is Crest Syndrome?

A
  • -Calcinosis
  • -Raynaud’s phenomenon
  • -Esophageal dysmotility
  • -Sclerodactyly
  • -Telangiectasia
28
Q

CREST Syndrome is associated w/ what arthropathy?

A

Scleroderma

29
Q

What seropositive arthropathy has retraction of the fingertips w/ resorption of the distal tufts?

A

Scleroderma

30
Q

What is Acro osteolysis?

A

Resorption of the distal bony phalanges

31
Q

What is the lab finding for seronegative arthropathies?

A

POSITIVE HLA-B27

32
Q

What are the 4 Seronegative RA variants?

A
  • -Psoriatic arthritis
  • -Enteropathic arthritis
  • -AS
  • -Reactive
33
Q

What is the most common seronegative RA variant?

A

AS

34
Q

AS is a chronic inflammatory condition most commonly affecting what populations?

A

Males

35
Q

Ankylosing Spondylitis is 100% involved in what joint?

A

SI joint

36
Q

How is Ankylosing Spondylitis differentiated from the other arthropathies affecting the SI joints?

A

Bilateral symmetric

37
Q

Ankylosing Spondylitis erosions present as what sign?

A

Rosary bead sign

38
Q

Ankylosing Spondylitis involving the upper SI will present with what sign?

A

Star sign

39
Q

How does AS affect the vertebral body?

A
  • -destroy corner of vertebral body
  • -squaring of vertebrae anteriorly
  • -ossification of outer annular fibers
40
Q

What seronegative RA variant presents as “bamboo spine?”

A

AS

41
Q

What seronegative RA variant presents as “Shiny corner sign?”

A

AS

42
Q

What is the difference between marginal and non-marginal?

A

Marginal = originates at vertebral margin

Non-marginal = originates mid-body

43
Q

What is a syndesmophyte?

A

Bony growth originating inside a ligament

44
Q

Radiographically what is the difference between marginal and non-marginal?

A

Marginal = thin

Non-marginal = thick

45
Q

What are 3 signs of AS at the apophyseal joints?

A

Erosion, sclerosis, loss of space

46
Q

If AS produces a “Trolly track sign,” what 4 ligaments will ossify?

A
  • -Capsule,
  • -Ligamentum Flavum
  • -Inter/supraspinous lig
47
Q

If AS produces a “Dagger sign,” what 2 ligaments will ossify?

A

Inter/supraspinous ligaments

48
Q

What 3 joints are affected w/ psoriatic arthritis?

A
  • -Peripheral joints
  • -SI
  • -Spine
49
Q

If you find arthritis affecting peripheral joints, SI, spine, and the patient has nail pitting what is the pathology?

A

Psoriatic Arthritis

50
Q

What joints in the hand are affected by psoriatic arthritis?

A

DIPs and PIPs

51
Q

What is it called if psoriatic arthritis 3 joints in the hand?

A

Ray pattern

52
Q

What type of pattern does psoriatic arthritis present as in the hands?

A

Asymmetric, joint widening, and erosion

53
Q

What do the marginal erosions of the psoriatic arthritis resemble?

A

Mouse ears

54
Q

What form of arthritis presents with:

  • -Conjuctivitis
  • -Urethritis
  • -Heel spur or retrocalcaneal bursitis
A

Reactive arthritis

55
Q

How does one distinguish the reactive arthritis from psoriatic arthritis?

A

Reactive primarily involves feet, psoriatic arthritis primarily involves hands

56
Q

What is the foot rash associated w/ reactive arthritis?

A

Keratoma blennorrhagica

57
Q

What are the 4 common sites involving CPPD?

A
  • -Knee (menisci)
  • -Wrist
  • -MCPs
  • -Symphysis pubis
58
Q

What is the most frequent joint for clinical and radiographic changes of CPPD?

A

Knee (menisci)

59
Q

If CPPD is in the wrist, it will present as a calcification of triangular cartilage in what joint?

A

Ulnar meniscial triquetral joint

60
Q

Hemochromatosis presents as a triad of what 3 things?

A
  • -cirrhosis
  • -diabetes
  • -bronze colored skin
61
Q

What radiographic sign will hemochromatosis present with in the hand?

A

MCP hook osteophytes

62
Q

What pathology presents w/ an “overhanging edge/margin” sign, at periarticular erosions?

A

Gout

63
Q

What 3 lab tests are used to determine seropositive/RA types?

A

Increased ESR, + ANA test, –HLA-B27

64
Q

What 3 lab tests are used to determine seronegative/RA variants?

A

Increased ESR, – ANA test, + HLA-B27