Inflammatory Diseases Flashcards
what is sympathetic ophthalmia?
bilateral granulomatous uveitis
causes of sympathetic ophthalmia?
trauma
surgery
how does sympathetic ophthalmia occur?
an autoimmune reaction to ocurlar antigens in BOTH eyes, even though one was injured
eyes are isolated from systemic immune system (immune priviledge)
what cells are involved in sympathetic ophthalmia?
CD4 then CD8
features of sympathetic ophthalmia?
blurred vision
discomfort
conjunctival infection
mutton fat keratic precipitates
what is scleritis?
inflam of the sclera
associations with scleritis?
RA
GPA
uveitis
features of scleritis?
pain
constant headache boring into eye
sore ocular movements
photophobia
signs of scleritis?
vessels do not move or blanche
violaceous hue
treatment of scleritis?
NSAIDs
steroids
what happens in GCA?
posterior ciliary artery becomes occluded
ischaemia of optic nerve
vision loss
histology of GCA
multinucleate giant cells
two causes of ischaemic optic neuropathy?
GCA
atherosclerosis
features of episcleritis?
not sore
ache
vessels move when touched
inflammatory nodule
causes of episcleritis?
gout
recurrent