Inflammatory Disease of The Skin Flashcards

0
Q

What are the two classifications of eczema?

A

Endogenous and exogenous

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1
Q

What is the genetic component of eczema?

A

Mutation on filaggrin chrom. 1

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2
Q

What are the types of endogenous eczema?

A

Atopic, seborrhoeic, discoid, varicose

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3
Q

What are the types of exogenous eczema?

A

Contact and photo reaction (due to allergy or drugs)

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4
Q

What blood levels are high in atopic eczema?

A

IgE

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5
Q

What type of hypersensitivity reaction is dermatitis?

A

Type IV

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6
Q

What are the different categories of hypersensitivity and an example of each

A

Type I - anaphylaxis
Type II - blood transfusion
Type III - serum sickness
Type IV - dermatitis

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7
Q

What is serum sickness?

A

A delayed (4-10 day) reaction to non-human protein

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8
Q

What are the complications of atopic eczema?

A
Bacterial infection - staph
Viral infection - molluscum
Tiredness
Growth reduction
Psychological impact
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9
Q

What is the management of atopic eczema?.

A

Emollients
Topical steroids
Bandages
Antibiotics

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10
Q

What are common allergens found in contact dermatitis?

A

Nickel
Chromate (cement)
Cobalt (dye)

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11
Q

What is seborrhoeic dermatitis?

A

Chronic scales skin condition which is often thought to be dandruff and is worse in HIV

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12
Q

What specific topical treatment can be used in seborrhoeic dermatitis?

A

Anti-yeast shampoo

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13
Q

What is venous dermatitis?

A

Dermatitis found on the skin overlying varicose veins

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14
Q

What is the definition of psoriasis?

A

A chronic relapsing and remitting skin condition which may appear at any age and affect any part of the skin

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15
Q

What causes psoriasis?

A

Tcell mediated autoimmune disease

16
Q

What diseases is psoriasis linked to? (4)

A

Psoriatic arthritis
Metabolic syndrome
Liver disease / alcohol abuse
Depression

17
Q

What are the types of psoriasis?

A

Plaque
Guttate
Pustular
Erythrodermic

18
Q

How is psoriasis managed?

A
Topical creams
Phototherapy
Acitretin 
Methotrexate
Ciclosporin
Infliximab
19
Q

What is Acitretin?

A

An oral retinoid

21
Q

What topical therapies are used in psoriasis?

A

Moisturisers
Steroids
Retinoids

22
Q

What are the features of pityriasis alba?

A

Dry rough skin in cheeks
Hypopigmenations
More common in non-Caucasians

23
Q

What is the treatment for impetigo?

A

Topical antiseptic

Oral Abx - erythromycin

24
Q

What are the features of mastocytosis?

A

Mast cells in skin
Wide spread ski inflammation
Mistaken for impetigo

25
What is the most common contact dermatitis in babies? What are the features of this?
Nappy rash Candida infiltration Treated with more nappy changes, avoid soaps and wipes, thick barrier protection (zinc), topical steroid + antifungals
26
What is molluscum contagiosum?
DNA pox virus infection | Resolves on its on or with antiseptic
27
What is tinae capitus?
Final infection of scalp
28
What are the clinical features of tinae capitas?
Diffuse scaling of scalp | Patchy alopecia
29
What is the treatment of tinae capitas?
Terbinafine
30
Where to babies get scabies?
Soles and palms | Nodules in axilla, umbilicus
31
What are t he triggers for acute urticaria in children?
``` Infection Infestation Injection drugs Inhalation of allergens Ingestion of allergens ```
32
What haemoangiomas are dangerous? What are the features? Why do you worrying?
Segmented haemoangiomas of infants Occur as plaque Associated with visceral lesions and other underlying abnormalities
33
What are the risk factors of haemoangiomas?
Pre-term | Low birth weight
34
What are the complications of haemoangiomas?
Impaired vision Ulceration Infection Severe pain
35
What is the treatment of haemoangiomas?
Propranolol
36
What it sturge weber syndrome?
Ipsilateral capillary malformation Pia mater malformation Ocular dysfunction in children
37
What is a Mongolian blue spot?
Blues grey pigmentation of skin which is a normal finding of black and Asian infants