Inflammatory Disease of The Skin Flashcards

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0
Q

What are the two classifications of eczema?

A

Endogenous and exogenous

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1
Q

What is the genetic component of eczema?

A

Mutation on filaggrin chrom. 1

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2
Q

What are the types of endogenous eczema?

A

Atopic, seborrhoeic, discoid, varicose

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3
Q

What are the types of exogenous eczema?

A

Contact and photo reaction (due to allergy or drugs)

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4
Q

What blood levels are high in atopic eczema?

A

IgE

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5
Q

What type of hypersensitivity reaction is dermatitis?

A

Type IV

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6
Q

What are the different categories of hypersensitivity and an example of each

A

Type I - anaphylaxis
Type II - blood transfusion
Type III - serum sickness
Type IV - dermatitis

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7
Q

What is serum sickness?

A

A delayed (4-10 day) reaction to non-human protein

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8
Q

What are the complications of atopic eczema?

A
Bacterial infection - staph
Viral infection - molluscum
Tiredness
Growth reduction
Psychological impact
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9
Q

What is the management of atopic eczema?.

A

Emollients
Topical steroids
Bandages
Antibiotics

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10
Q

What are common allergens found in contact dermatitis?

A

Nickel
Chromate (cement)
Cobalt (dye)

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11
Q

What is seborrhoeic dermatitis?

A

Chronic scales skin condition which is often thought to be dandruff and is worse in HIV

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12
Q

What specific topical treatment can be used in seborrhoeic dermatitis?

A

Anti-yeast shampoo

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13
Q

What is venous dermatitis?

A

Dermatitis found on the skin overlying varicose veins

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14
Q

What is the definition of psoriasis?

A

A chronic relapsing and remitting skin condition which may appear at any age and affect any part of the skin

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15
Q

What causes psoriasis?

A

Tcell mediated autoimmune disease

16
Q

What diseases is psoriasis linked to? (4)

A

Psoriatic arthritis
Metabolic syndrome
Liver disease / alcohol abuse
Depression

17
Q

What are the types of psoriasis?

A

Plaque
Guttate
Pustular
Erythrodermic

18
Q

How is psoriasis managed?

A
Topical creams
Phototherapy
Acitretin 
Methotrexate
Ciclosporin
Infliximab
19
Q

What is Acitretin?

A

An oral retinoid

21
Q

What topical therapies are used in psoriasis?

A

Moisturisers
Steroids
Retinoids

22
Q

What are the features of pityriasis alba?

A

Dry rough skin in cheeks
Hypopigmenations
More common in non-Caucasians

23
Q

What is the treatment for impetigo?

A

Topical antiseptic

Oral Abx - erythromycin

24
Q

What are the features of mastocytosis?

A

Mast cells in skin
Wide spread ski inflammation
Mistaken for impetigo

25
Q

What is the most common contact dermatitis in babies? What are the features of this?

A

Nappy rash
Candida infiltration
Treated with more nappy changes, avoid soaps and wipes, thick barrier protection (zinc), topical steroid + antifungals

26
Q

What is molluscum contagiosum?

A

DNA pox virus infection

Resolves on its on or with antiseptic

27
Q

What is tinae capitus?

A

Final infection of scalp

28
Q

What are the clinical features of tinae capitas?

A

Diffuse scaling of scalp

Patchy alopecia

29
Q

What is the treatment of tinae capitas?

A

Terbinafine

30
Q

Where to babies get scabies?

A

Soles and palms

Nodules in axilla, umbilicus

31
Q

What are t he triggers for acute urticaria in children?

A
Infection
Infestation
Injection drugs
Inhalation of allergens 
Ingestion of allergens
32
Q

What haemoangiomas are dangerous? What are the features? Why do you worrying?

A

Segmented haemoangiomas of infants
Occur as plaque
Associated with visceral lesions and other underlying abnormalities

33
Q

What are the risk factors of haemoangiomas?

A

Pre-term

Low birth weight

34
Q

What are the complications of haemoangiomas?

A

Impaired vision
Ulceration
Infection
Severe pain

35
Q

What is the treatment of haemoangiomas?

A

Propranolol

36
Q

What it sturge weber syndrome?

A

Ipsilateral capillary malformation
Pia mater malformation
Ocular dysfunction in children

37
Q

What is a Mongolian blue spot?

A

Blues grey pigmentation of skin which is a normal finding of black and Asian infants