Inflammatory Bone Disorders Flashcards

1
Q

How does alveolar osteoitis occur?

Dry socket

A

Post-dental extraction complication in healing – Failure of blood clot formation, premature clot loss or clot disintegration which leads to localised inflammation of bone

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Which teeth are the most susceptible to dry socket?

A

Mandibular molars

More likely in difficult extractions

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What are some predisposing factors for dry socket?

A
  • Smoking
  • Poor OH
  • Oral contraceptive use (female)
  • Difficult extraction – Mandibular molars most susceptible
  • Active or recent acute ulcerative gingivitis or periodontitis
  • Previous history of dry socket following XLA
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Describe the presentation of healing in a patient with dry socket

A

Slow & delayed healing with granulation tissue proliferation from surrounding vital bone

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What may a patient complain of with dry socket?

A

Severe pain developing 2-3 days following extraction & progressively worsening
Foul smell
Foul taste
Halitosis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

What is the managment of dry socket?

A

Gentle socket irrigation with saline or chlorhexidine
Pack with Alvogyl
Analgesic advise/prescribe
Radiograph – Exclude possibility of retained root fragments or foreign body
OH advice & review

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What are the contents of Alvogyl?

A

Contents:
LA (pain relief)
Iodine (antiseptic)
Eugenol (obtundent)

obtundent = reducing irritation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

What organisms can cause osteomyelitis?

A

Staphylococcus
Streptococcus
Escherichia coli
Neisseria gonorrhoea
Haemophilus influenza

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

What are some sources of infection for osteomyelitis?

A

1) Haematogenous – Rare in jaws but may occur in children

2) Non-Haematogenous – Open wounds (e.g. dental extraction, surgery or fracture), direct spread from blood stream or middle ear infection

Haematogenous = Originitating from blood

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

What are some local predisposing factors of osteomyelitis?

A

Decreased vascularity or vitality (e.g. due to trauma)
Irradiation (exposed to radiation)
Bisphosphonate medication
Paget’s disease*
Osteoporosis (weakened bones)

*disrupts the normal cycle of bone renewal, causing bones to become weak

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What are some systemic predisposing factors of osteomyelitis?

A

Immunodeficiency
Diabetes
Leukaemia
Agranulocytosis*
Systemic corticosteroids
Chemotherapy
Extremities of age

*deficiency of granulocytes in blood, more vulnerability to infection

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

What is this?

A

Dry Socket

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

What is this?

A

Dry Socket

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

What is this?

A

Osteomyelitis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

What symptoms may a patient with osteomyelitis present with?

What would you see clinically?

A

Pain, swelling, pyrexia, malaise, trismus, paraesthesia with altered sensation

Exposed necrotic bone +/- suppuration with discharge of pus through one or more intra- oral or extra-oral sinuses

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

What is this?

A

Osteomyelitis

17
Q

What are the different classifications of osteomyelitis?

A

Acute/Pyogeneic osteomyelitis
Chronic osteomyelitis (further broken down to)
1. SUB-PERIOSTEAL GARRE’S – Young children following dental abscess
2. SCLEROSING (LOCALISED/GENERALISED)

18
Q

What is the managment of osteomyelitis?

A

Specialist referral - Surgery & IV antibiotics

19
Q

What are some possible complications of osteomyelitis?

A

Septicaemia (blood poisoning)
Acute bacterial arthritis
Pathological jaw fracture

20
Q

What is Osteoradionecrosis?

A

Radiation affects bone vascularity by causing proliferation of the intima of blood vessel walls

The consequence is loss of vitality to the bone

intima = inner lining of blood vessel wall

21
Q

What is the presentation of osetoradionecrosis?

A

If bone remains sterile then it is asymptomatic

If infected it will lead to osteomyelitis

22
Q

What is the management of a patient with osteoradionecrosis?

A

Hyperbaric oxygen therapy
Surgical resection & reconstruction
Anti-radiation fibrosis & Anti-oxidant medication

23
Q

What medications can lead to MRONJ?

A
  1. Bisphosphonates
  2. RANKL Inhibitors
  3. Anti-angiogenics