Inflammation Process Flashcards
What are the 5 cardinal signs of inflammation?
redness heat swelling pain functional loss
Define inflammation?
Inflammatory response, the local response of the body to an injury or irritant
What are the duel functions of inflammation?
- Defend body against foreign substances
2. Dispose of dead and dying tissues so that repair can take place.
The primary signs of inflammation always occur in response to an injury, the ______ and ______ on a person’s level of ______ depends on the ______, ______ of injury, and ______ of activity.
magnitude impact activity extent location nature
What is the best example of inflammation that Jenn and the book gave you??
Knight defending from invaders, laborers cleaning up the debris so wall can be rebuilt.
How many events are in the inflammation process?
8
In order, name all the events of the inflammatory process
- injury
- ultrastructural changes
- chemical mediators
- hemodynamic changes
- metabolic changes
- permeability changes
- leukocyte migration
- phagocytosis
Inflammation process: injury
an occurrence that impairs the structure or function of tissue & alters cell’s ability to carry out it’s normal homeostatic mechanisms.
What are the causes of injury??
physical agents
metabolic processes
biological agents
chemical agents
Orthopedic injuries
finish
Define trauma
“a wound”, 2 types, injury that results from physical force.
- Macrotrauma
- microtrauma
Macrotrauma
"impact or contact injury" large stress, results in immediate tissue disruption. Acute Injuries -Primary injuries -Secondary injuries
Acute injury
Macrotrauma or “impact or contact injury”
Large stress, results in immediate tissue disruption
Microtrauma
“overuse, cyclic loading, friction injury”
caused by small or low-grade stress that wears on tissue over time.
Chronic Injuries
Chronic Injuries
Microtrauma, “overuse, cyclic loading, friction injuries”
caused by small or low grade stress that wears on tissue over time.
Inflammatory Process: Ultrastructural changes
Breaking/disruption of cellular membranes & organelles.
Cells die, cell’s membrane & contents becomes debris, bust be removed before repair can take place.
What are the 2 different ways of causing structural damage and causing accumulation of debris?
Primary injury and Secondary injury
Primary Injury
DIRECTLY results from physical force
Secondary injury
INDIRECTLY result of metabolism or chemical injury, husband in cells adjacent to those undergoing primary injury.
Direct result of physical force
Primary injury
Indirectly result of metabolism or chemical injury, occurs in cells adjacent to those undergoing primary injury
Secondary injury
Inflammation Process: Chemical Mediatoion
Histamine, bradykinin, and cytokine are activated by ultrastructueral changes. Signal rest of body that cells are dosage movie, mobilize body’s resource to respond the regulate rest of !-)
What is the example of chemical mediation example?
Police officers, the can give..
Inflammation Process: Hemodynamic changes description
Transports blood borne defenses to injury site. Occur in healthy blood vessel’s and periphery blood vessels.
Inflammation Process: Hemodynamic changes.
Blood flow increase -> inactive capillaries/venules open for increase BF -> rate of flow in individual vessels is slowed -> slowing of flow rate lets the leukocytes work -> move from center of vessels to vessel walls (endothelium) -> leukocytes pass through ndothelium gas
