Inflammation Process Flashcards

1
Q

What are the 5 cardinal signs of inflammation?

A
redness
heat
swelling 
pain
functional loss
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2
Q

Define inflammation?

A

Inflammatory response, the local response of the body to an injury or irritant

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3
Q

What are the duel functions of inflammation?

A
  1. Defend body against foreign substances

2. Dispose of dead and dying tissues so that repair can take place.

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4
Q

The primary signs of inflammation always occur in response to an injury, the ______ and ______ on a person’s level of ______ depends on the ______, ______ of injury, and ______ of activity.

A
magnitude
impact
activity 
extent
location 
nature
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5
Q

What is the best example of inflammation that Jenn and the book gave you??

A

Knight defending from invaders, laborers cleaning up the debris so wall can be rebuilt.

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6
Q

How many events are in the inflammation process?

A

8

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7
Q

In order, name all the events of the inflammatory process

A
  1. injury
  2. ultrastructural changes
  3. chemical mediators
  4. hemodynamic changes
  5. metabolic changes
  6. permeability changes
  7. leukocyte migration
  8. phagocytosis
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8
Q

Inflammation process: injury

A

an occurrence that impairs the structure or function of tissue & alters cell’s ability to carry out it’s normal homeostatic mechanisms.

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9
Q

What are the causes of injury??

A

physical agents
metabolic processes
biological agents
chemical agents

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10
Q

Orthopedic injuries

A

finish

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11
Q

Define trauma

A

“a wound”, 2 types, injury that results from physical force.

  • Macrotrauma
  • microtrauma
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12
Q

Macrotrauma

A
"impact or contact injury"
large stress, results in immediate tissue disruption.
Acute Injuries
-Primary injuries
-Secondary injuries
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13
Q

Acute injury

A

Macrotrauma or “impact or contact injury”

Large stress, results in immediate tissue disruption

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14
Q

Microtrauma

A

“overuse, cyclic loading, friction injury”
caused by small or low-grade stress that wears on tissue over time.
Chronic Injuries

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15
Q

Chronic Injuries

A

Microtrauma, “overuse, cyclic loading, friction injuries”

caused by small or low grade stress that wears on tissue over time.

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16
Q

Inflammatory Process: Ultrastructural changes

A

Breaking/disruption of cellular membranes & organelles.

Cells die, cell’s membrane & contents becomes debris, bust be removed before repair can take place.

17
Q

What are the 2 different ways of causing structural damage and causing accumulation of debris?

A

Primary injury and Secondary injury

18
Q

Primary Injury

A

DIRECTLY results from physical force

19
Q

Secondary injury

A

INDIRECTLY result of metabolism or chemical injury, husband in cells adjacent to those undergoing primary injury.

20
Q

Direct result of physical force

A

Primary injury

21
Q

Indirectly result of metabolism or chemical injury, occurs in cells adjacent to those undergoing primary injury

A

Secondary injury

22
Q

Inflammation Process: Chemical Mediatoion

A

Histamine, bradykinin, and cytokine are activated by ultrastructueral changes. Signal rest of body that cells are dosage movie, mobilize body’s resource to respond the regulate rest of !-)

23
Q

What is the example of chemical mediation example?

A

Police officers, the can give..

24
Q

Inflammation Process: Hemodynamic changes description

A

Transports blood borne defenses to injury site. Occur in healthy blood vessel’s and periphery blood vessels.

25
Q

Inflammation Process: Hemodynamic changes.

A

Blood flow increase -> inactive capillaries/venules open for increase BF -> rate of flow in individual vessels is slowed -> slowing of flow rate lets the leukocytes work -> move from center of vessels to vessel walls (endothelium) -> leukocytes pass through ndothelium gas