Inflammation

Question 1

Basophils

Answer 1

Blue-staining granulocytes that carry an IgE receptor and contain cytoplasmic granules filled with biologically active enzymes and cytokines that mediate the inflammatory process.

Question 2

Chronic Inflammation

Answer 2

Inflammation of more than two weeks duration characterized by the presence of mononuclear cells and often associate with endogenous infectious agents such as viruses or intracellular bacteria or the presence of a foreign body.

Question 3

Edema

Answer 3

Swelling of tissue.

Question 4

Eosinophils

Answer 4

Red-staining granulocytes that contain biologically active proteins and enzymes that mediate defense against parasitic infections. Eosinophils also produce cytokines that down-regulate the inflammatory response, remodel extracellular matrix during tissue healing, and mediate many adverse responses during asthmatic attacks and allergic reactions to pharmaceuticals.

Question 5

Erythema

Answer 5

Redness of the skin associated with inflammation.

Question 6

Granulocytes

Answer 6

A major group of white blood cells that have irregular, lobed nuclei and granules in their cytoplasm.

Question 7

Granulomas

Answer 7

Areas of tissue damage caused by chronic inflammation characterized by large areas of tissue destruction surrounded by fibrous elements of extracellular matrix and the presence of large, bizarre inflammatory cells.

Question 8

Inflammation

Answer 8

The localized election that occurs in tissue in response to an infection of physical or chemical injury.

Question 9

Leukocytes

Answer 9

White blood cells.

Question 10

Lymphocytes

Answer 10

A subgroup of mononuclear cells that includes the T and B cells that mediate acquired immune reactions.

Question 11

Mast Cells

Answer 11

Cells that are similar to basophils in form and function that originate in the bone marrow and migrate to connective tissue surrounding blood vessels.

Question 12

Monocytes

Answer 12

A subgroup of mononuclear cells that are called monocytes when they are on the bloodstream and macrophages when they are in tissues. These cells are the APC’s that mediate endocytosis and presentation of antigen to T and B cells during immune reactions.

Question 13

Mononuclear Cells

Answer 13

A major group of white blood cells that have round non-segmented nuclei and smooth cytoplasm.

Question 14

Neutrophils

Answer 14

Non-staining granulocytes that contain digestive endoscopes and are the principal mediators of phagocytosis in acute inflammation.

Question 15

Permeability

Answer 15

A porous condition or state of cells or tissues that allows liquids to pass through them.

Question 16

Phagocytes

Answer 16

Cells capable of phagocytosis including neutrophils, monocytes, and macrophages.

Question 17

Platelets

Answer 17

Specialized blood cells that interact with coagulation proteins in the blood to form clots and stop bleeding from damaged blood vessels.

Question 18

Polymorphonuclear Leukocyte (PMN)

Answer 18

Another term for granulocyte.

Question 19

Acute Inflammation

Answer 19

Inflammation of less than two weeks duration often associated with bacterial infections and usually characterized by the presence of granulocytes, principally neutrophils.