Inflammation

Question 1

What is inflammation?

Answer 1

Natural protective immune response to harmful stimuli (e.g. infections, injury, toxins, necrotic cells)

Question 2

Name the 2 types of inflammation.

Answer 2

1. Acute inflammation
2. Chronic inflammation

Question 3

List the 5 steps of acute inflammatory response.

Answer 3

1. Recognition
2. Recruitment of leukocytes
3. Removal of harmful agent
4. Regulation of the response
5. Repair

Question 4

Which leukocytes are recruited in acute inflammatory response?

Answer 4

Mainly neutrophils.

Macrophages come later & replace neutrophils.

Question 5

Clinical presentation of acute inflammation

Answer 5

Local cardinal signs - redness, warmth, pain, swelling, loss of function

Systemic signs - fever, high WBC count, elevated acute-phase proteins

Question 6

What is the role of histamine in inflammation?

Answer 6

Causes vasodilation, increases vascular permeability, and promotes allergic responses

Question 7

List the types of acute inflammation

Answer 7

1. Serous inflammation
2. Fibrinous inflammation
3. Suppurative inflammation & abscess
4. Ulceration