inflammation Flashcards
Cox 1
Involved in many body functions (normal):
Blood clotting, Protecting stomach lining, kidney
Good cox
Cox 2
Active at site of trauma or injury (inflammation)
Pain, inflammation, vasodilation, bleeding
bad cox
acetaminophen
reduces fever & pain. No anti-inflammatory benefit
adverse effects for acetaminophen
liver failure
nursing considerations for acetominophen
4 grams max daily dose
Acetylcysteine antidote for OD
salicytate
aspirin
use for salicylates
low dose (81mg) prevents CVA/MI
adverse effects of salicylates
GI bleeding
nursing considerations for salicylates
give with food and encourage hydration
patient education for salicylates
hold at least 1 week before and after surgery
propionic acid derivatives
ibuprofen
adverse effects of propionic acid derivatives
GI effects
GI bleeding
oxicam derivatives
meloxicam
adverse effects for meloxicam
black box: GI bleeding and MI
acetic acid derivatives
indomethacin