endocrine Flashcards

1
Q

antithyroid drugs

A

propylthiouracil (PTU)

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2
Q

adverse effects for antithyroid drugs

A

black box: liver failure

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3
Q

thyroid drugs

A

levothyroxine

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4
Q

nursing considerations for thyroid drugs

A

take in the morning on an empty stomach

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5
Q

factors that stimulate the pituitary

A

○ Corticotropin-releasing hormone (CRH)
○ Growth hormone releasing hormones (GHRF)
○ Thyroid-releasing hormone (TRH)
○ Gonadotropin-releasing hormone (GnRH)
Prolactin-releasing hormone (PRH)

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6
Q

factors that inhibit the pituitary

A

Somatostatin (Growth hormone release-inhibiting factor)

Prolactin-inhibiting factor (PIF)

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7
Q

what does Corticotropin-releasing Hormone (CRF) do

A

release of corticotropin during stress

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8
Q

what does growth hormone-releasing hormone (GHRH) do

A

release of growth hormones

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9
Q

what does thyroid-releasing hormone (TRH) do

A

releases TH during stress

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10
Q

what does gonadotropin-releasing hormone (GnRH) do

A

releases FSH and LH

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11
Q

what does prolactin-relasing hormone (PRF) do

A

lactation and childbirth

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12
Q

what does prolcatin-inhibiting factor (PIF) do

A

inhibits lactation

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13
Q

pituitary gland

anterior lobe (6)

A

releases:
GH
ACTH
FSH
LG
PRL
TSH

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14
Q

pituitary gland

posterior lobe (2)

A

stores
ADH (vasopressin)
oxytocin

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15
Q

anterior pituitary hormone actions

Corticotropin (ACTH)

A

Stimulates production of corticosteroids

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16
Q

anterior pituitary hormone actions

growth hormone AKA somatotropin (GH)

A

stimulates growth of body tissues

17
Q

anterior pituitary hormone actions

thyroid stimulating hormone (TSH)

A

regulates secretion of thyroid hormones

18
Q

anterior pituitary hormone actions

follicile stimulating hormone

A

stimulates functions of sex lands

19
Q

anterior pituitary hormone actions

luteninizin hormone (LH)

A

stimulates hormone production

20
Q

anterior pituitary hormone actions

prolactin hormone (PH)

A

milk production in mothers

21
Q

posterior pituitary hormone actions

antidiurtic hormone AKA vasopressin (ADH)

A

reulates water balance

22
Q

anterior pituitary hormone actions

oxytocin

A

uterine contractions, milk letdown

23
Q

Drug Therapy for Growth Deficiency

A

Somatropin

24
Q

contraindications for Drug Therapy for Growth Deficiency

A

closed epiphyses - the cessation of the growth of a particular bone

25
Q

Drug Therapy for Diabetes Insipidus

A

Desmopressin (DDAVP)

26
Q

advserse effects for Drug Therapy for Diabetes Insipidus

A

Black box warning: cardiac arrest d/t rapid fluid volume change

Black box warning: risk of hyponatremia leading to seizures & death

27
Q

Signs and Sx of hypocalcemia

A

CNS: hyperactive relflexes, parethesias, positive chvostek and trousseau signs
CV: Hypotension, prolonged QT interval, edema, signs of cardiac insufficency
GI: abdominal spasms and cramps
Muscular: tetany, skeletal muscle cramps, layngael spasm
Skeletal: bone pain, osteomalacina, bone defromities, fractures

28
Q

signs and Sx of hypercalcemia

A

CNS: lethargy, personaility changes, stupor, coma
CV: hypertension, shortened QT iternal, AV block
GI: anorexia, N/V, constipation
Muscular: weakness, atrophy, ataxia, loss of muscle tone
Renal: polyuria, flank pain, kidney stones, acute/chronic renal insufficency
Skeletal: osteopenia, osteoporosis

29
Q

treatment for hypocalcemia

A

calcium supplements

calcium acetate, calcium carbonate (tums), calcium citrate, calcium glu

30
Q

contraindications for calcium supplements

A

kidney stones

31
Q

treatment for hypercalcemia (bisphosphonates)

A

alendronate

32
Q

adverse effects of bisphophonates

A

esophageal irritation / erosion

33
Q

contraindictions for bisphosphonates

A

inability to sit upright for 30 mins

34
Q

nursing considerations fo bisphosphonates

A

If unable to sit upright for 30 mins will need to take Calcitonin Salmon instead

35
Q

drugs for addisons disease

A

fludrocortisone

36
Q

adverse effects of drugs for addisons disease

A

fluid retention
HTN
CHF

37
Q

drug therapy for cushings disease

A

ketoconazole

38
Q

nursing considerations for drugs for cushings disease

A

give with an acidic liquiud

OJ or coffee