infertility, conception through pregnancy Flashcards
FSH: follicle stimulating hormone
Stimulates the follicle (which houses the eggs) to grow and mature
LH-luteinizing hormone
After ovulation, converts the empty follicle into the corpus luteum and supports this structure(which in turn supports an early pregnancy until the placenta forms)
estrogen
stimulates uterine growth and uteroplacental blood flow, cases a proliferation of the breast glandular tissue and stimulates myometrial contractility (at term)
progesterone
The hormone of pregnancy-
- maintains the endometrium
- decreases the contractility of the uterus
- stimulates maternal metabolism and development of breast alveoli
relaxin
relaxes the ligaments in the pelvis and softens and widens the cervix.
prostaglandins
PGE: vasodilatory; smooth muscle relaxant (for uterine growth)
PGF: vasoconstrictive; smooth muscle contractor (for labor)
GnRH
- what shows up on pregnancy test
- once egg is fertilized in uterine linning
human chorionic gonadotropin
- high levels at beg of preg
- lower at end
- HCG starts being produced after implantation
- Remains low for duration of pregnancy
- Levels can be checked to evaluate state of pregnancy
- This is the hormone pregnancy tests test for
- HCG can also be tested by blood test, certain levels (amounts) correspond to weeks of gestation.
- If someone is miscarrying or having a pregnancy abnormality (ectopic preg, hydatidiform mole, genetic abnormality) then levels would be off what they should be at that gestation. - Multifetal pregnancies may cause increased levels of HCG
HCG peaks at
60-70 days of gestation (weeks 8-10)
hcg declines at
100-130 days of pregnancy (14- 19 weeks)
infertility
inability to get preg for <12m
reasons for infertility
- decrease sperm
- endometriosis
- ovulation disorders
- tubal occlusion
intrauterine insemination
procedure use to place prepared sperm in the uterus at the time of ovulation
in vitro fertiliation- embryo transfer
procedure of collecting clients eggs from the ovaries, fertiliizing the eggs in the labatory with sperm, and transfering the embryo to the uterus
gamete intrafallopian transfer
- oocytes are retrieved and immediately placed with prepared motile sperm. both are placed together into a thin flexible tube. gametes are than injected into the fallopian tubes using surgical labroscopy
donor oocyte
donated eggs are collected from a donor by IVF. eggs are inseminated. embroyos are placed in a recipents uterus. prior to implantation, the recipient undergoes hormonal therapy to prepare the uterus
donor embryo
donated embryo is placed in the recipients uterus, which is hormonally prepared
gestational carrier
couple completes the process fo IVF with the embryo placed in aother person, who will carry the preg. this is a contract agreement with the carrier having no genetic investment with the embryo
surrogate mother
person is inseminated with semen and carries the fetus untill birth
therapeutic donor insemination
donor sperm is used to inseminate a person
embryonic development
The embryonic stage lasts from day 15 after fertilization until 8 weeks. All organ systems and external features are developing during this time. This is the most critical time, where the embryo is most vulnerable to malformations caused by environmental teratogens.
- happens after fertilization
embryoblast
becomes baby
blastocyst
embrotic cavity
trophoblast
membrane and placenta