Infertility, ART, and Recurrent Pregnancy Loss Flashcards
Infertility definition
One year of unprotected intercourse without conception
What percent of men with less than 5 million sperm/mL have a deletion in Yq
4%
3 methods to treat male factor infertility
Intrauterine insemination. therapeutic donor insemination, ICSI
What are the 2 options for controlled ovarian hyperstimulation
Clomid and injectable gonadotropins
What are 3 genetic aetiologies for disorders of ovulation?
Fragile X permutation carrier, X-chromosome abnormalities, PCOS
What day are embryos typically selected on for IVF?
Day 5
What type of genetic disorders are more likely in IVF pregnancies?
Imprinting Disorders
Definition of recurrent pregnancy loss
2 or more failed clinical pregnancies as documented by u/s or histopathologic exam
What percent of couples with RPL have major chromosome rearrangements?
4%