Infertility Flashcards
1
Q
3 classes of infertility
A
1) Ovulatory 30%
2) Male factor 25%
3) Fertilisation 30%
2
Q
Ix of ovulatory problems?
A
Mid luteal progesterone
Serial USS
LH urine
3
Q
Causes of anovulation?
A
PCOS Hypothalamic hypogonadism Prolactinoma Thyroid disease POI
4
Q
Drug to stimulate ovulation?
A
Clomiphene!
5
Q
Male factors?
A
Varicocoele (25%) Prolactinoma Klinefelter's CF Mumps orchitis
6
Q
Mx of male factor
A
If tubes are ok - IUI
If no patent tubes - IVF with ICSI
7
Q
Ix of male factors
A
Semen analysis
See if count or motility is the problem
8
Q
Fertilisation factors?
A
Tubal damage - PID, surgery, endometriosis, adhesions
Cervical problems - infection, inadequate mucus due to cone biopsy
Sexual problems
9
Q
Investigation of tubes?
A
Hysterosalpingogram
10
Q
AMH for?
A
Measure of ovarian reserve
11
Q
What happens in IVF?
A
1) 2 weeks daily SC FSH and LH injections
2) Single LH injection to trigger final maturation
3) TV follicle aspiration
