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Cardiac Pathology > Infective Endocarditis > Flashcards

Infective Endocarditis Flashcards

1
Q

General

A

Bacteremia –> bacteria invades valve –> Vegetation formation

Vegetation: Bacteria/Necrosis/Cell Debris/Inflmm Cells

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2
Q

Classification of IE

A

1) Acute EC:

  • Highly Virulent (staph A) + Normal Valve destruction

2) Subacute EC:

  • Low Virulence (strep.viridens) + previously deformed valve
    • ABX therapy => Recovery
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3
Q

Pathogenesis

A

Usually Immune system deals with the bacteria but if there are Pre-disposing factors such as:

  1. RF
  2. Cardiac Malformation
  3. Prosthetic Valves
  4. Host Factors:​

​- malignancy

  • alchohol/IV drug use
  • DM
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4
Q

Causative Agents

A
  1. Staph . A
  2. Strep Viridens
  3. HACEK (hemophilus/ Actinobact/ Cardiobacter/ Eikenella/ Kingella)
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5
Q

Source of Micro-organism

A
  1. Dental/ Surgical Procedure
  2. Injection of Contaminated Material
  3. Portal Entry
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6
Q

Complication of Infective Endocarditis

A
  1. Embolization
  2. Perforation of Valve
  3. Ring Abscess
  4. AG in Circ –> IC formation:

​- Renal Failure

  • Vasculitis
  • Joint problems
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Cardiac Pathology (6 decks)

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