Infectious Mononucleosis

Question 1

Infectious Mononucleosis Causative Pathogens

Answer 1

• 90% EBV

- 10% not EBV, mostly CMV

Question 2

Infectious Mononucleosis Presentation

Answer 2

• Most have few symptoms
• Low grade fever, fatigue and malaise
• Sore throat
• Exudative and large tonsils
• Palatal petechiae and uvular oedema
• Transient upper lid oedema
• Lymphadenopathy

Question 3

Infectious Mononucleosis Differentials

Answer 3

• GAS (does not have posterior cervical, inguinal or axillary adenopathy, palatine petechiae, splenomegaly or atypical lymphocytosis
• Bilateral periorbital oedema may also be due to Kawasaki

Question 4

Infectious Mononucleosis Investigations

Answer 4

• Test heterophile antibodies first

- If still negative after 6 weeks with an IM illness, test for EBV specific antibodies

Question 5

Infectious Mononucleosis Associated Diseases

Answer 5

• Burkitt’s

- Hodgkins

Question 6

Infectious Mononucleosis Management

Answer 6

• Paracetamol
• Avoid contact sports
• Avoid alcohol
• Steroids if airway obstruction