Infectious Mononucleosis Flashcards

1
Q

What is infectious mononucleosis commonly known as?

A

Infectious mononucleosis is also known as glandular fever.

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2
Q

What virus primarily causes infectious mononucleosis?

A

Infectious mononucleosis is caused by the Epstein-Barr virus (EBV) in 90% of cases.

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3
Q

What are less frequent causes of infectious mononucleosis?

A

Less frequent causes include cytomegalovirus and HHV-6.

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4
Q

In which age group is infectious mononucleosis most common?

A

It is most common in adolescents and young adults.

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5
Q

What is the classic triad of symptoms for infectious mononucleosis?

A

The classic triad includes sore throat, pyrexia, and lymphadenopathy.

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6
Q

What is lymphadenopathy in infectious mononucleosis?

A

Lymphadenopathy may be present in the anterior and posterior triangles of the neck.

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7
Q

What are other features of infectious mononucleosis?

A

Other features include malaise, anorexia, headache, palatal petechiae, splenomegaly, hepatitis, lymphocytosis, and haemolytic anaemia.

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8
Q

What percentage of patients develop a rash when taking ampicillin/amoxicillin?

A

A maculopapular, pruritic rash develops in around 99% of patients who take ampicillin/amoxicillin.

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9
Q

How long do symptoms of infectious mononucleosis typically last?

A

Symptoms typically resolve after 2-4 weeks.

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10
Q

What test is used for diagnosing infectious mononucleosis?

A

The heterophil antibody test (Monospot test) is used for diagnosis.

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11
Q

What does NICE recommend for confirming a diagnosis of glandular fever?

A

NICE guidelines suggest FBC and Monospot in the 2nd week of the illness.

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12
Q

What is the management approach for infectious mononucleosis?

A

Management is supportive, including rest, hydration, and simple analgesia.

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13
Q

What is the consensus guidance regarding contact sports after glandular fever?

A

It is advised to avoid playing contact sports for 4 weeks to reduce the risk of splenic rupture.

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14
Q

What correlation exists between EBV and socioeconomic groups?

A

Lower socioeconomic groups have high rates of EBV seropositivity, while higher socioeconomic groups show a higher incidence of infectious mononucleosis.

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