Infectious diseases Flashcards

1
Q

Which diseases should be routinely screened for in pregnancy in Australia?

A

HIV, Rubella, Hep B, Syphilis, Varicella, Group B strep and Urine culture

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2
Q

What are the 6 most common non-STI’s?

A
UTI
Bacterial vaginosis
Candidiasis
Group B Strep
Hep B & C
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3
Q

What are the 7 most common STI’s?

A
Chlyamydia
Gonorrhea
HSV Type 2
HIV
HPV
Syphilis
Trichomoniasis
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4
Q

How common is asymptomatic bacteriuria, and how often will it convert to symptomatic UTI or pyelonephritis in pregnancy?

A

Present in 2-10% of women, and converts in 20 - 30% of pregnant women.

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5
Q

What is the treatment and management of UTI’s in pregnancy?

A
Antibiotics for 7-10 days;
Increase fluids 1.5-2L per day;
Educate on hygiene;
Reduce simple sugars in diet and eat yoghurt or other probiotics while taking antibiotics;
Educate on S/S for women to report.
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6
Q

What are the three main types of infections of the vagina and vulva?

A

Bacterial vaginosis
Trichomoniasis
Candidiasis

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7
Q

What are the S/S of BV, the treatment, and risks for pregnancy?

A

S/S - thin, grey/white discharge, may have fishy odour
Treated with antibiotics
Increases risk of spontaneous abortion, PROM, TPL, LBW. Can cause neonatal septicaemia and postpartum endometritis.

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8
Q

What is Trichomoniasis and how is it treated?

A

It is an infection by a protozoan is usually sexually transmitted.

S/S - perineal itching, profuse discharge that may be frothy, yellow/green or grey with a foul odour, dyspareunia, mild dysuria and lower abdo pain.

Treat with antibiotics

Implicated in PROM, LBW and preterm delivery

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9
Q

What is candidiasis and how is it treated/managed?

A

Common fungal infection. Highest rates in third trimester.

S/S - vaginal and vulva irritation, itching, white curd-like discharge, yeasty odour, dysuria and dyspareunia.

Treat with antifungal suppository or cream.

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10
Q

Chlamydia is the most common cause of PID, and is most common among people younger than 25. T or F

A

True

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11
Q

Chlamydia is asymptomatic in _____ % of cases.

A

60 - 80.

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12
Q

Up to ________% of babies born to mothers infected with Chlamydia will become infected.

A

70

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13
Q

Which states are showing a rise in syphilis rates?

A

NT and QLD

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14
Q

What is the affect of syphilis on pregnancy?

A

May infect the fetus (if untreated - almost 100% infection rate), cause spontaneous abortion, preterm birth, death. Can increase HIV transmission (particularly if genital ulcer present).

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15
Q

What is early onset GBS infection?

A

Infection presenting within the first 7 days of life. Late onset occurs from 7 days to 90 (three months).

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16
Q

When in pregnancy should GBS screening occur?

A

Between 35-37 weeks.

Not required if Hx of previous child with EOGBS or if GBS bacteriuria in pregnancy (NSW Health policy)

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17
Q

In pregnancy, HPV warts tend to ________?

A

Proliferate and become friable.

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18
Q

What are the S/S of genital herpes (HSV - 2)

A

Intense pain, dysuria, occasional itching, vaginal discharge, fever, headache, nausea, malaise, myalgia.

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19
Q

When does HSV-2 pose a risk to the fetus?

A

A primary occurence in the third trimester poses a risk of infection to the neonate (potentially fatal). Otherwise safe to have a NVB.

20
Q

How is HSV-2 treated?

A

Aciclovir in pregnancy.

21
Q

A mother that carries Hep B has a ______% chance of infecting her baby.

22
Q

How is transmission of Hep B to the fetus prevented?

A

All babies receive a Hep B immunisation at birth, aswell as Hep B immunoglobulins (85%-95% effective).

23
Q

How is Hep C usually transmitted?

A

IV drug use, accidental needle stick and blood transfusions.

24
Q

What care is required for a woman with Hep C?

A

Routine antenatal care with baseline liver function assessment;
Avoid ARM and FSE in labour.

25
What is the risk of transmission of HIV without treatment?
Without antiretroviral therapy the transmissions rates are approx 20- - 25%. With treatment for mother and baby, transmission rates can be 1% or less.
26
Can a woman with HIV have a NVB?
Depends on viral load at onset of labour or ROM - if undetectable and on antirerovirals then can proceed. Otherwise can elect LSCS at 38 weeks. Breastfeeding is contraindicated.
27
Maternal rubella infection in the first 16 weeks can cause ___________?
Fetal death, LBW, deafness, cataracts, jaundice, congenital heart disease, microcephaly and intellectual disability.
28
How is listeriosis contracted, and what is the risk?
Contaminated food such as meat and dairy; Preterm birth, neonatal sepsis or stillbirth.
29
How can toxoplasmosis be acquired?
Ingestion of undercooked meats, ingestion of oocytes excreted by cats, mother to child transmission in pregnancy, or transplanted organs/blood products. Over 50% of women may be asymptomatic.
30
When is the transmission of toxoplasmosis to the fetus most likely?
Highest risk in third trimester (stillbirth), however teratogenetic effects weeks 10 - 24 such as visual and hearing loss, mental and psychomotor retardation, seizures, haematological abnormalities or stillbirth.
31
What symptoms may be present for Chlamydia?
Vaginal discharge or abnormal bleeding Abdo pain and fever Infertility or ectopic pregnancy Dysuria
32
How is chlamydia diagnosed and treated?
By endocervical swab or 1st void urine and lower vaginal swab. Treat with Azithromycin and retest in 1 month
33
How is syphilis diagnosed and treated?
Diagnosed with blood test (note can have false positive in pregnancy) Treat with penicillin.
34
Gonnorrhea is asymptomatic in ____% of people
80
35
If Gonno is left untreated what can happen?
Can affect tubal patency and fertility, upper genital tract infection In pregnancy - increased risk of preterm birth; infection of neonate at birth
36
How is Gonno treated?
250mg of Ceftriaxone
37
What are the symptoms of listeriosis?
Fever, headache, tiredness, aches & pains. Possibly diarrhea, nausea and abdo cramps.
38
How is listeriosis treated?
penicillin or amoxyl/ampicilin
39
How is BV treated?
Single dose of metronidazole.
40
How is GBS infection treated?
Pencillin is preferred or ampicillin 1.2g of Benzyl Penicillin followed by 600mg 4hourly until birth
41
A baby born to a HIV infected mother should be bathed immediately and NOT given any IM injections. T or F.
True
42
60% of confirmed early onset GBS in the neonate occurs to women with a negative GBS culture. T or F?
True
43
What are the risk factors for early-onset GBS infection?
``` Hx of infant with EOGBS GBS infection at any time in pregnancy Preterm in established labour Maternal pyrexia (>= 38 S/S of suspected chorioamnionitis ROM for 18 hours or more. ``` For any of these factors - recommend IAP.
44
Should a woman planning an elective LSCS be screened for GBS?
Yes - SROM and colonisation can still occur prior to planned LSCS. However, IAP not required if membranes intact at time of LSCS - only if SROM or contractions prior to LSCS.
45
What is the management for detection of EOGBS in the neonate?
In all cases - 4/24 observations for baby! If term gestation well baby with mother receiving IAP and no risk factors in labour or hx then no treatment. 4/24 observations If sibling hx or symptoms of maternal infection in labour - 4 hourly assessments of baby for 24 hours, consider for another 24 hours. Medical review to determine if antibiotics for baby needed. If well baby without IAP given - 4 hrly assessment for 24 hrs, then consider additional 24hrs. Preterm well baby with IAP - 4/24 observations and assess for further 24 hrs.