Infectious Diseases

Question 1

Paragonimus kellicotti: Distribution and vector

Answer 1

World wide, particularly US (Great Lakes, Midwest, South)
Crayfish

Question 2

Paragonimus kellicotti: Type

Answer 2

Trematode lung fluke

Question 3

Paragonimus kellicotti: Pathogenesis

Answer 3

Migrates intestine -> peritoneum -> crosses diaphragm -> pleural space -> subpleural tissues -> eosinophilic and neutrophilic inflammation
Form bullae and cysts through parenchyma
Mature flukes access bronchioles via network of ‘tunnels’, allowing ova to be coughed up and swallowed to permit faecal shedding

Question 4

Paragonimus kellicotti: Most affected lung lobe

Answer 4

Right caudal

Question 5

Paragonimus kellicotti: Treatment

Answer 5

Fenbendazole, praziquanel
Treatment of pneumo/haemothorax

Question 6

Filaroides: Type

Answer 6

Nematode

Question 7

Paragonimus kellicotti: Pathogenesis

Answer 7

Ovoviviparous parasite, direct faeco-oral transmission, reside in alveolar spaces and terminal bronchioles
Diffuse bronchointerstitial and alveolar infilrates