Infectious Diseases Flashcards

1
Q

HIV

Best initial test to diagnose HIV?

A

4th generation assay
or
NAAT

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2
Q

HIV

What does 4th generation assay detect As HIV diagnostic tool?

A

Detect HIV Ag that appears before Ab

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3
Q

HIV

What if you have 4th generation test + and negative differentiation assay. Next step?

A

NAT.

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4
Q

HIV

Confirmatory test for HIV?

A

Differentiation assay

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5
Q

HIV

Examples of NRTI

A

Dida, Stav, Zid and lama, tino and abacavir

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6
Q

HIV

Which NNRTI causes dehydration?

A

Indinavir causes nephroplethiasis and dehydration

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7
Q

HIV

Screen for HLAB-5701 before introducing this medication

A

Abacavir

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8
Q

HIV

HIV medication causes low PO, AKI, and osteoporosis

A

Tinofovir

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9
Q

HIV

Integrase inhibitor CI in T1

A

Dolutegravir

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10
Q

HIV

Which ART causes GI upset and proteinuria

A

LV Elvitegravir

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11
Q

Virology

Immigrant presented with fever, rash started behind his ears then descend to the feet + white rash in his mouth

A

Measles. This is Koplik spot.
Note: rash spares palms and soles.

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12
Q

Virology

Most common cause of death in measles?

A

Pneumonia

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13
Q

Virology

Management of a child with contact to patient with measle infection?

A

MMR vaccine within 72 hours.

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14
Q

Virology

Patient came from brazil with fever for 2 days. Then improve for 2 days then cameback with fever + hemametemesis and jaundice. Diagnosis?

A

Yellow fever.
Know it by: Hemorrhagic fever + remission period.

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15
Q

Virology

4 etiology of hemorrhagic fever

A

Ebola, lassa virus, Dengue fever and yellow fever

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16
Q

STD

Patient presented with painless beefy genital ulcer without LAP

A

Donovaniosis

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17
Q

STD

Painful single genital ulcer + Painful LAP

A

Chancroid (H. Ducrei)
Multiple painful = HSV

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18
Q

STD

Painless genital ulcer with painful LAP

A

LGV

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19
Q

STD

Name this complication. Seen in which phase of syphilis?

A

Condyloma latum. In second phase.
Note: condyloma accuminata seen with anogenital warts.

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20
Q

Vaccines

PHC nurse took HBV Vaccine one month ago. She came not to test for Anti-HBV load. The result was 50. Next step?

A
  • Give another booster dose of HBV.
  • This result means there is response but incomplete which need only one extra dose.
  • If < 10: Need new Vaccine course.
  • If > 100: She is fine and next step is vaccination after 5 years
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21
Q

HIV

What is the role of HIV RNA test?

A

Limited. Used only to screen blood donor and infants.

22
Q

Malaria

What is the benifit of adding Primaquin in malaria Rx?

A

Destroy liver hypnozyte which prevent disease relapse.

23
Q

Malaria

In which malaria species we need to add Primaquine?

A

Only Vivax and Ovale.

24
Q

Malaria

Indication of blood exchange in malaria ?

A

Parasitemia > 10 %

25
# Parasitology Fever, throat congestion, cervical LAP for 2 weeks. Negative EBV. History of BBQ one week ago
Acute toxoplasmosis. Which mimic infectious mononuclosis
26
# Parasitology Patient came from brazil. With skin ulcer on lower limb + in the mouth + fever. Etiology?
Leshmania Brazilinies. Skin only: Mexico + Tropicalis Visceral: Donovani (Kala-azar disease)
27
# Parasitology Treatment of persistent lymphadenopathy in immunocompetent patient with positive serology for toxoplasmosis?
No treatment required.
28
Most common location for aspiration pneumonia?
Right lower lobe | posterior segment of R Up. lobe + superior segment of R lower lobe
29
Which leishmania associated with visceral disease?
Donovanosis. Require bone marrow aspiration for diagnosis. Others: 1) Brazili: mucucotaneous 2) mexico: Cutaneous
30
Which leishmania associated with visceral disease?
Donovanosis. Require bone marrow aspiration for diagnosis. Others: 1) Brazili: mucucotaneous 2) mexico: Cutaneous
31
Disease spectrum of anthrax
1) GI bleeding 2) Wide mediastium and respiratory failure 3) most important. Painless skin eschar. Remember painless !!
32
When to give the vaccines for encapsulated organisms before elective splenectomy?
2 weeks prior to the surgery
33
Patient came from Tanzania 2 weeks ago presented with fever, maculopapular rash, LAP. Diagnosis? How to confirm?
HIV-1 Diagnosis: RNA, PCR. At this stage Ab are negative
34
Mechanism of action of oseltemavir?
Nueroaminidase inhibitor
35
RIF pain, diarrhea. Diagnosis?
Pseusdo appendicitis. Campylobacter. Remember: It causes GBS Treatment: clarithromycin
36
EEG pattern for temporal encephalitis?
Lateralized periodic discharge at 2 Hz
37
EEG pattern for temporal encephalitis?
Lateralized periodic discharge at 2 Hz
38
Which vaccine should be avoided in patient with egg allergy?
Yellow fever.
39
2 stains used for PJP diagnosis?
1- Silver stain 2- Giemsa stain
40
HIV patient on ART, Presented with nail blackish color. Which medication can cause this?
Ziduvodine
41
HIV patient on ART, Presented with nail blackish color. Which medication can cause this?
Ziduvodine
42
Sabin feldman dye test. Used to detect which infection?
Toxoplasmosis
43
Patient on ART. Presented with jaundice and isolated increase in bilirubin. Normal ALT, AST. What medication cause this?
Atazanavir (Protease inhibitor)
44
- 18 years old male with fever 38.5, cervical LAP, pharyngitis with exudate and negative heterophile antibody test With no leukocytosis + presence of atypical lymphocytosis.
EBV. As 25 % will have negative test
45
Sun burn rash in young female patient in palmes and soles + fever + hypotension.
Staphylococcus toxic shock syndrome
46
47
Patient had car accident with metal penetration to his arm. His last tetanus vaccine was 7 years ago. What is your next step?
No Immunoglobulin, no vaccine if the last dose was less than 10 years ago.
48
Peri-anal skin urticarial rash migrates to the thigh. Diagnosis?
Strongyloides stercoralis
49
Chest infection and bradycardia. Organism?
Legionella. Treat with clarithromycin
50
Chest infection and bradycardia. Organism?
Legionella. Treat with clarithromycin