Infectious Diseases Flashcards
1
Q
What is acquisition of infection influenced by
A
- Immune status
- Pathogenicity of microbe
- Infectious dose
- Portal of entry
2
Q
How do microbes avoid phagocytosis
A
- Toxins that kill phagocyte
- Hide antigenic surface
- Avoid direct contaact
3
Q
How do microbes interfere with ciliary action
A
- Production of ciliostatic substances
- Destroy ciliated cells
4
Q
How do microbes interfere with complement activation
A
- Gain or mimic complement regulators
- Active inhibition
- Destruction
- Block lysis
5
Q
How do microbes survive adaptive immunity
A
- Silent invasion
- Persisting in host
- Hit and run
- Elude lymphocytes
6
Q
How do microbes conceal antigens
A
- Mimcry
- Cover surface using host molecules
7
Q
How does HIV evade the immune response
A
- High replication number, high mutation rate, antigenic variation
- Use some host cell membrane as its own
- Variable sugars
- Latency
- CD4 T cells as targets
