INFECTIOUS DISEASES Flashcards
Which medication can cause a rash in patients with glandular fever?
Amoxicillin
What will be seen on Hep B serology during an acute infection?
HBsAg (HB surface antigen) +ve
Anti-HBsAg -ve
Anti-HBcAg IgM +ve
Anti-HBcAg IgG +/-ve
What will be seen on Hep B serology during a chronic infection?
HBsAg +ve
Anti-HBsAg -ve
Anti-HBcAg IgM -ve
Anti-HBcAG IgG +ve
What will be seen on Hep B serology indicating previous infection and current imunity?
HBsAg -ve
Anti-HBsAg +ve
Anti-HBcAg IgM -ve
Anti-HBcAg IgG +ve
When should HIV +ve patients receive prophylaxis for PCP?
CD4 count <200
Co-trimoxazole (septrin)
Which test is used for the diagnosis and screening of HIV?
Combination tests (HIV p24 antigen and HIV antibody)
What is the management of an animal bite in a high risk country?
the wound should be washed
if an individual is already immunised then 2 further doses of vaccine should be given
if not previously immunised then human rabies immunoglobulin (HRIG) should be given along with a full course of vaccination.
If possible, the dose should be administered locally around the wound
Diarrhoea and hypoglycaemia is indicative of which infective disease?
Cholera
What is the first-line treatment for early Lymes disease?
14-21 day course of oral doxycycline
What is the most common cause of food poisoning in the UK?
Campylobacter jejuni
What is the incubation period of staph aureus gastroenteritis?
1-6 hours
What is the incubation period of salmonella typhi gastroenteritis?
16-48 hours
What causes travellers diarrhoea?
E.coli
What is the incubation period of Giardia duodenalis?
7 days
When is the tetanus vaccine given in the UK?
2 months 3 months 4 months 3-5 years 13-18 years
If a tetanus vaccination history is unknown, how should wounds be treated?
- reinforcing dose of vaccine, regardless of the wound severity
- for tetanus prone and high-risk wounds: reinforcing dose of vaccine + tetanus immunoglobulin
What antibiotics are used for sepsis?
Empirical broad spec
Which abx are used in neutropenic sepsis?
Tazocin
Which abx are used in typical pneumonia?
Amoxicillin
Which abx are used in severe pneumonia?
Amoxicillin & macrolide
Which abx are used in a lower UTI?
Nitrofurantoin
Trimethoprim
What abx are used for pyelonephritis?
Cefalexin/co-amoxiclav
What abx are used for cellulitis?
Flucloxacillin
What abx are used for an animal bite?
Co-amoxiclav
What are the abx used in tonsillitis?
Penicillin V (phenoxymethylpencillin)
Otitis media abx?
Amoxicillin
Sinusitis abx?
Penicillin V
SBP abx?
Tazocin
C.diff abx?
ORAL Vancomycin
+IV metronidazole if life-threatening
fidoxamicin if recurrent
Septic arthritis abx?
Empirical IV abx
Flucloxacillin & rifampicin