infectious disease prevention and control Flashcards
early 20th century leading causes of death
respiratory diseases (e.g tuberculosis and diarrheal diseases were major killers)
what is a leading causes of death world in children wide and second leading cause of death overall?
infectious disease
current infectious disease concerns
HIV, pneumonias and influenza, VRSA, MRSA, SARS
latent period
time delay between exposure and onset of contagiousness (ability to spread pathogen to others)
incubation period
time delay between exposure and onset of disease signs and symptoms
communicable period
contagious time, when person to person transmission is possible
sporadic disease
disease that occurs occasionally in a population
endemic disease
disease constantly present in a population
epidemic disease
disease beyond normal expected rates in one region or community
pandemic disease
worldwide epidemic
stages of infection in populations
case, cluster/outbreak, epidemic, pandemic
index case
the first case identified in a population
primary case
the person that brings the infection into a population
secondary case
someone who is infected by a primary case
tertiary case
someone who is infected y a secondary case
chain of infection
reservoir, portal of exit, mode of transmission, portal of entry, susceptible host
reserviors of infection are continual (or potential) sources of infection.
- human
- animal
- nonliving
human- AIDS, gonorrhea (carriers may have subclinical infections or latent diseases)
animal- rabies, lyme disease (some zoonotic diseases may be transmitted to humans
nonliving- botulism, tetanus, legionnaires disease (soil or water)
west nile virus in children
often asymptomatic
west nile virus in elderly
a lot of subclinical cases will have severe sx
host response: infection
the entry and multiplication of an infectious agent in a host (sometimes subclinical, usually symptomatic)
- incubating the organism (pre-disease)
- disease
- convalescing from exposure to the organism (post-disease)
colonization
presence of an organism in a host
host carrier state
colonization without apparent disease but can often spread disease (a lot of nurses are carriers for MRSA)
concerns about carriers: numbers
carriers may outnumber cases. contribute to high prevalence of disease
concerns about carriers: hard to identify
carriers do not have symptoms to determine if they should be tested
concerns about carriers: mobility
carriers are healthy and often mobile, cases are sick and often their mobility is restricted
concerns about carriers: chronicity
carriers can have infection later in life, re-introduce infection to those who were previously cleared and contribute to endemic disease
vertical transmission
mom to baby