Infectious Disease Flashcards
What are penicillins good at treating?
strep/staph, syphilis
What is vanco good at covering?
gram-pos and c. diff (PO)
What are macrolides good at covering?
atypicals and ppl with PCN allergy
What is clindamycin used for?
additional anearobic coverage
What are common SE of flouroquinolones?
prolonged QT, cartilage damage, tendon rupture
What are common SE of aminoglcosides?
ototoxicity (irreversible), nephrotoxicity (reversible)
What are aminoglucycosides good at covering?
gram-neg
What is metronidazole good at covering?
anaerobes and C. diff
Patient who is a cattle farmer presents with black eschar rash, pneumonia and N/V/D
anthrax
What is anthrax?
gram-pos spore-forming rod
What is tx of anthrax?
cipro or doxy
Patient returns from mexico and has bloody diarrhea, fever, maliase, abd pain
salmonella
How do you tx salmonella?
cipro x2 weeks
What is presentation of shigella?
diarrhea, cramps
How do you treat shigella?
only if severe, bactrim or flouroquinolone
Patient presents with rice water stools, and no fecal odor
cholera
How do you tx cholera?
macrolide
How do you dx rocky mountain spotted?
ELISA then western blot
How do you treat rocky mountain spotted?
doxycycline
Where do you see tularemia?
Arkansas, Oklahoma
How do you treat tularemia?
gentamicin or tetracycline
How do you dx malaria?
blood smear
What is tx of malaria?
chloroquine
Patient has multiple ring-enhacing lesion son CT scan
toxoplasmosis
What is tx of toxoplasmosis?
pytimethamine and sulfadiazine
Patient presents with bloody diarrhea and hepatic abscess
amebiasis
What is tx of amebiasis?
metronidazole
Patient presents after camping with diarrhea and greasy foul smelling stools w/o blood
giardia
What is tx for giardia?
metronidazole
What is associated with schistosomiasis?
snails
What is assocaited with infected pork?
trichinosis
What do you treat worms with?
albendaole and mebendazole
When is someone considered to have AIDS?
CD4 under 200 or AIDS-defining condition
CD4 under 200 diseases
Kaposi sarcoma, TB, oral thrush, PCP, lymphoma, oral hairy leukoplakia
How do you treat PCP pna?
bactrim
What causes kaposi sarcoma?
human herpes virus 8 (HHV8)
CD4 under 100 diseases
toxoplasmosis, cryptococcosis, disseminated candida
CD4 under 50
CMV, MAC
How do you treat CMV?
gangciclovir
How do you treat MAC?
macrolide
philadelphia chormosome
CML
How do you treat CML?
imatinib, chemo, BM transplant
Aure rods
AML
what age does AML usually occur?
over 60yo
Which leukemia is tolerated well for years?
CLL
How do you treat CLL?
rituximab, prednisone, fludarabine
What age does ALL affect?
kids usually
What is multiple myeloma?
malignant plasma cells
What sxs are associated with multiple myeloma?
hyperCa, fx, renal failure, anemia
When do you see bence jones proteins?
multiple myeloma
how do you treat multiple myeloma?
clacitonin, biphosphonates, alkylating agents, thalodomide, prednosone, BM transplant
What is caused by antibodies against platelets causing thrombocytopenia?
ITP
What is tx for ITP?
steroids acutely, IVIG, splenectomy
Patient presents with renal failure, hemolytic anemia, thrombocytopenia, and neuro changes and fever
TTP/HUS
What are risk factors for TTP/HUS?
E. coli 0157:H7
What is treatment for TTP/HUS?
plasmaphoresis, FFP
What shouldn’t you do in TTP/HUS?
platelet transfusions
When does HIT occur?
5-10 days after exposure to heparin
What is treatment of HIT?
anticoag (argatroban, dabigatran)
basophilic stippling
sideroblastic anemia
What causes sideroblastic anemia?
lead poisoning