Infectious Disease Flashcards
Which bacterial organisms causing disease are intracellular?
Chlamydia
Mycoplasma (pneumoniae)
Ureaplasma
Which antibiotics act on cell walls?
Be Good
Beta lactams
prevent peptidoglycan crosslinkage:
Penicillins, Cephalosporins, Carbapenems
Glycopeptides
Inhibit peptidoglycan synthesis
Vancomycin, Teicoplanin
Which types of antibiotics act on ribosomes?
And Tickle Molly
30S:
Aminoglycosides (gentamycin)
Tetracycline
50S:
Erythromycin (macrolide), Clindamycin
How do fluoroquinolone antibiotics work?
be good and tickle molly for sweets, treats and QUICK rewards
Inhibits supercoiling by DNA
Patient with swollen glands and a sore throat is given Amoxicillin and gets a red rash all over their body. What has happened?
EBV + Amoxicillin = drug eruption
Not a penicillin allergy
Which antibiotic causes grey staining of teeth?
Tetracyclines
What side effect of rifampicin should patients be warned about?
Orange secretions/pee
Why do you do an eye test before commencing TB medication?
Ethambutol can cause irreversible optic atrophy and blindness
Isoniazid causes reduced red-green perception
Gram negative intracellular diplococci?
Neisseria
Alcohol dependency confirmed by medical enquiry requires driving licence revocation for how long?
When would a vocational driving licence not be granted because of alcohol?
Until a one year period of abstinence has been attained.
If in the last 3 years, someone has been alcohol dependent
Doctor gets a needle stick, can you take blood from an unconscious patient in ITU to check if they were HIV +ve?
Only if it’s in the patient’s best interests, not for the doctor’s sake
Doctor gets a needle stick from an ITU patient who then dies, can you take blood from them to see if they were HIV +ve?
Only if family/next of kin agrees
What is excluded as a disability under equalities act?
If the primary problem is alcohol or drug addiction or pyromania
But if you get psoriasis secondary to alcohol addiction it does count
What conditions are automatically considered a disability under the equalities act?
MS, cancer, HIV, blindness
Alcohol dependency confirmed by medical enquiry requires driving licence revocation for how long?
When would a vocational driving licence not be granted because of alcohol?
Until a one year period of abstinence has been attained.
If in the last 3 years, someone has been alcohol dependent
Patient in history had a 1cm red swelling that great to 5cm and became ulcerated with a reddish margin. Likely cause?
Cutaneous Leishmania
(Via sandfly inoculating it with a promastigote)
Lesions heal spontaneously
Persistent unremitting fever and pinkish spots on trunk after going to India.
(Fever, headache abdo pain also)
Typhoid
Fever once established won’t go down until treated
Visited middle east, now abdo cramps, increased frequency of micturition and episodes of haematuria. Urine dip = protein ++ blood ++ Likely cause + Rx?
Schistozomiasis
Rx: Praziquantel
What is the different between typhus and typhoid?
Typhoid is caused by Salmonella typhus = unremitting fever, rose spots on trunk, unusual bradycardia with fever
Typhus is caused by rickettsia bacteria = often transmitted via tick bite, mild rash or life threatening meningococcal septicaemia
Organism responsible for pityriasis versicolor?
Malassezia furfur (fungal)
Tick bite leading to haemorrhagic rash and hepatosplenomegaly. Causative organism?
Rickettsia (typhus)
What things make cause a malarial infection to be considered ‘severe’?
Low consciousness, 2+ convulsions in 24 hours
Acidosis, hypoglycaemia
